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比较不同环境中的脂质膜。

Comparing lipid membranes in different environments.

作者信息

Akabori Kiyotaka, Nagle John F

机构信息

Department of Physics, Carnegie Mellon University , Pittsburgh, Pennsylvania 15213, United States.

出版信息

ACS Nano. 2014 Apr 22;8(4):3123-7. doi: 10.1021/nn501499t. Epub 2014 Apr 14.

DOI:10.1021/nn501499t
PMID:24730729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4052381/
Abstract

When engineering lipid membranes for applications, it is essential to characterize them to avoid artifacts introduced by manipulation and the experimental environment. Wide-angle X-ray scattering is a powerful structural characterization tool for well-ordered lipid systems. It reveals remarkable differences in rotational order parameters for samples prepared in different ways. New data and perspectives are presented here for multilamellar systems that support and extend the characterization work on unilamellar systems that is reported by Watkins et al. in this issue of ACS Nano.

摘要

在设计用于各种应用的脂质膜时,对其进行表征以避免操作和实验环境引入的假象至关重要。广角X射线散射是用于有序脂质系统的强大结构表征工具。它揭示了以不同方式制备的样品在旋转序参数方面的显著差异。本文给出了关于多层系统的新数据和观点,这些数据和观点支持并扩展了沃特金斯等人在本期《美国化学会纳米》杂志上报道的关于单层系统的表征工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/75ca595ff38c/nn-2014-01499t_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/75ed3f6f9edf/nn-2014-01499t_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/44788ee41500/nn-2014-01499t_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/901b83afb80f/nn-2014-01499t_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/75ca595ff38c/nn-2014-01499t_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/75ed3f6f9edf/nn-2014-01499t_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/44788ee41500/nn-2014-01499t_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/901b83afb80f/nn-2014-01499t_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1c3/4052381/75ca595ff38c/nn-2014-01499t_0004.jpg

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Formation and analysis of topographical domains between lipid membranes tethered by DNA hybrids of different lengths.
不同长度 DNA 杂交体连接的脂双层之间的拓扑结构域的形成和分析。
Faraday Discuss. 2013;161:333-45; discussion 419-59. doi: 10.1039/c2fd20108a.
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Structure and properties of tethered bilayer lipid membranes with unsaturated anchor molecules.具有不饱和锚定分子的束缚双层脂质膜的结构和性质。
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