离子通道与G蛋白。
Ion channels and G proteins.
作者信息
Brown A M, Birnbaumer L
机构信息
Baylor College of Medicine, Houston.
出版信息
Hosp Pract (Off Ed). 1989 Jul 15;24(7):189-93, 198, 202-4. doi: 10.1080/21548331.1989.11703753.
Abstract
Newly discovered relationships offer insight into the mechanisms by which extracellular signals produce complex cellular responses. Ion channels, serving crucial cellular functions, are now known to be gated by G proteins directly (by membrane-delimited processes) and indirectly (by cytoplasmic second messengers). It also appears that a G protein may act on several effectors.
摘要
新发现的关系为深入了解细胞外信号产生复杂细胞反应的机制提供了线索。离子通道在细胞功能中起着关键作用，现在已知它们可由G蛋白直接（通过膜限定过程）和间接（通过细胞质第二信使）进行门控。似乎G蛋白还可能作用于多种效应器。
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