Tolmunen Tommi, Lehto Soili M, Julkunen Juhani, Hintikka Jukka, Kauhanen Jussi
Department of Psychiatry, Institute of Clinical Medicine, University of Eastern Finland, Finland; Department of Psychiatry, Kuopio University Hospital, Finland.
Department of Psychiatry, Institute of Clinical Medicine, University of Eastern Finland, Finland; Department of Psychiatry, Kuopio University Hospital, Finland.
Ann Epidemiol. 2014 Jun;24(6):463-8. doi: 10.1016/j.annepidem.2014.03.001. Epub 2014 Mar 21.
We aimed to examine the impact of anxiety and somatic concerns on the mortality risk during a 23-year follow-up of a representative sample of men.
Finnish men aged 42-61 years (n = 2388) were followed up for a median of 23.4 years. Anxiety was assessed using baseline scores for the Minnesota Multiphasic Personality Inventory Psychasthenia subscale and somatic concerns were measured with the Hypochondriasis subscale. Mortality data were obtained from the National Population Register.
All-cause, injury, disease, cardiovascular, and cancer mortalities were examined as endpoints. Adjustments were performed for age, smoking, alcohol consumption, physical activity, low- and high-density lipoprotein cholesterol, body mass index, systolic blood pressure, a history of cardiovascular disease, marital status, socioeconomic status, the Framingham Type A Behavior Pattern Scale, and life events during the 12 months before the baseline examination. Anxiety and somatic concerns predicted the all-cause mortality risk after full adjustments for sociodemographic background, lifestyle factors, and descriptors of somatic health. Regarding other forms of mortality, the risk ratios were significant after full adjustments in anxiety for injury and in somatic concerns for disease death.
This study supported previous findings of anxiety predicting the all-cause mortality risk in men. Somatic concerns are a novel factor that needs to be taken into account while examining associations between personality and the risk of increased mortality.
我们旨在研究焦虑和躯体担忧对一组具有代表性的男性样本进行23年随访期间死亡风险的影响。
对年龄在42 - 61岁的芬兰男性（n = 2388）进行了中位时间为23.4年的随访。焦虑程度使用明尼苏达多相人格调查表精神衰弱分量表的基线得分进行评估，躯体担忧则用疑病分量表进行测量。死亡数据来自国家人口登记册。
将全因死亡率、损伤死亡率、疾病死亡率、心血管疾病死亡率和癌症死亡率作为终点进行考察。对年龄、吸烟、饮酒、体育活动、低密度和高密度脂蛋白胆固醇、体重指数、收缩压、心血管疾病史、婚姻状况、社会经济地位、弗雷明汉A型行为模式量表以及基线检查前12个月内的生活事件进行了调整。在对社会人口学背景、生活方式因素和躯体健康指标进行全面调整后，焦虑和躯体担忧可预测全因死亡风险。对于其他形式的死亡率，在对焦虑与损伤死亡率以及躯体担忧与疾病死亡风险进行全面调整后，风险比具有显著性。
本研究支持了先前关于焦虑可预测男性全因死亡风险的研究结果。躯体担忧是一个新的因素，在研究人格与死亡率增加风险之间的关联时需要加以考虑。
