Zhao Cuiqing, Tao Xifeng, Lei Bingkai, Zhang Yifan, Li Gen, Lv Yuanyuan, Yu Laikang
Division of Physical Education, Myongji University, Seoul 03674, Republic of Korea.
Beijing Key Laboratory of Sports Performance and Skill Assessment, Beijing Sport University, Beijing 100084, China.
Curr Oncol. 2025 May 25;32(6):304. doi: 10.3390/curroncol32060304.
This study aims to investigate the effects of exercise on depression and anxiety in lung cancer survivors and identify the optimal exercise prescription for this population. Searches were conducted in PubMed, Web of Science, Cochrane Library, Embase, Scopus, CNKI, and Wanfang Data up to 7 January 2024. A meta-analysis was performed to calculate the standardized mean difference (SMD) and 95% confidence interval. Thirteen studies were included in this meta-analysis. Exercise significantly alleviated depression (SMD, -0.54; = 0.002) and anxiety (SMD, -0.66; = 0.0002) in lung cancer survivors. Subgroup analyses showed that aerobic exercise, exercise conducted >3 times per week, <60 min per session, and ≥180 min per week, were more effective in alleviating depression and anxiety, particularly in middle-aged individuals. In conclusion, exercise alleviates depression and anxiety in lung cancer survivors, particularly those who are middle-aged, and aerobic exercise may be the most effective intervention. This meta-analysis provides clinicians with evidence to recommend that lung cancer survivors engage in exercise more than three times per week, with each session lasting less than 60 min, aiming to achieve a total of 180 min per week by increasing the frequency of exercise.
本研究旨在调查运动对肺癌幸存者抑郁和焦虑的影响，并确定该人群的最佳运动处方。截至2024年1月7日，在PubMed、科学网、考克兰图书馆、Embase、Scopus、中国知网和万方数据中进行了检索。进行了一项荟萃分析以计算标准化平均差（SMD）和95%置信区间。本荟萃分析纳入了13项研究。运动显著减轻了肺癌幸存者的抑郁（SMD，-0.54；P = 0.002）和焦虑（SMD，-0.66；P = 0.0002）。亚组分析表明，有氧运动、每周进行超过3次、每次少于60分钟且每周不少于180分钟的运动，在减轻抑郁和焦虑方面更有效，尤其是在中年个体中。总之，运动可减轻肺癌幸存者的抑郁和焦虑，尤其是中年幸存者，有氧运动可能是最有效的干预措施。这项荟萃分析为临床医生提供了证据，建议肺癌幸存者每周进行超过三次运动，每次运动持续时间少于60分钟，通过增加运动频率，每周总计达到180分钟。
