一名绝经后中国女性的纯非妊娠性子宫绒毛膜癌经短串联重复序列分析得以确诊。

Pure nongestational uterine choriocarcinoma in a postmenopausal Chinese woman confirmed with short tandem repeat analysis.

作者信息

Wang Yingmei, Yang Yufang, Teng Fei, Zhang Huiying, Xue Fengxia

机构信息

Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.

Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China; Department of Gynecology and Obstetrics, Tianjin People's Hospital, Tianjin, China.

出版信息

Am J Obstet Gynecol. 2014 Jul;211(1):e1-3. doi: 10.1016/j.ajog.2014.04.013. Epub 2014 Apr 13.

DOI:10.1016/j.ajog.2014.04.013

PMID:24732004

Abstract

Nongestational choriocarcinomas have been observed in the ovaries but rarely the uterus in postmenopausal women. Choriocarcinomas of gestational and nongestational origin have distinct prognoses but cannot be distinguished with routine histologic examination. We report a case of nongestational uterine choriocarcinoma in a 62-year-old Chinese woman that was confirmed with short tandem repeat analysis.

摘要

非妊娠性绒毛膜癌在绝经后女性的卵巢中较为常见，但在子宫中很少见。妊娠性和非妊娠性起源的绒毛膜癌预后不同，但通过常规组织学检查无法区分。我们报告了一例62岁中国女性的非妊娠性子宫绒毛膜癌病例，该病例通过短串联重复序列分析得以确诊。