Hoffmayer Kurt S, Dewland Thomas A, Hsia Henry H, Badhwar Nitish, Hsu Jonathan C, Tseng Zian H, Marcus Gregory M, Scheinman Melvin M, Gerstenfeld Edward P
Division of Cardiology, Section of Electrophysiology, University of Wisconsin, Madison, Wisconsin.
Division of Cardiology, Section of Electrophysiology, University of California, San Francisco, California.
Heart Rhythm. 2014 Jul;11(7):1117-21. doi: 10.1016/j.hrthm.2014.04.019. Epub 2014 Apr 13.
Ventricular arrhythmias (VAs) originating from the aortic root are common. Coronary angiography is typically recommended before catheter ablation to document proximity of the ablation catheter to the coronary ostia.
To investigate how often catheter ablation in the aortic root could be guided by phased-array intracardiac echocardiography (ICE) and electroanatomic mapping without requiring aortography or coronary angiography.
We reviewed consecutive patients referred for aortic root VAs to operators experienced in the use of ICE at a single center. An ICE catheter and a 3.5-mm irrigated ablation catheter were used in all cases, and the need for angiography before ablation was documented. Acute success and acute and 30-day complications were noted.
Thirty-five patients (age 58 ± 13 years; 74% men) were referred for the ablation of VAs; 32 of 35 (91%) underwent ablation using ICE and 3-dimensional mapping without the need for coronary angiography. Successful acute ablation was achieved in 29 of 35 (83%) patients. In all cases, the catheter tip was directly visualized with ICE >1 cm from the coronary ostia. The site of origin of the earliest VA was the left cusp (17 of 35 [49%]), right cusp (9 of 35 [26%]), right-left cusp junction (8 of 35 [23%]), or right-noncoronary cusp junction (1 of 35 [3%]). There were no cases of coronary injury, embolic stroke, aortic root perforation, worsening of aortic regurgitation, or death acutely or at 30 days.
Radiofrequency ablation of VAs originating from the aortic root may be safely performed using ICE and electroanatomic mapping in the majority of cases without the need for coronary angiography.
起源于主动脉根部的室性心律失常(VAs)很常见。通常建议在导管消融术前进行冠状动脉造影,以记录消融导管与冠状动脉口的接近程度。
研究在不进行主动脉造影或冠状动脉造影的情况下,相控阵心内超声心动图(ICE)和电解剖标测能在多大程度上指导主动脉根部的导管消融。
我们回顾了在单一中心被转诊至有ICE使用经验的术者处进行主动脉根部室性心律失常消融的连续患者。所有病例均使用ICE导管和3.5毫米灌注消融导管,并记录消融术前是否需要造影。记录急性成功率以及急性和30天并发症情况。
35例患者(年龄58±13岁;74%为男性)被转诊进行室性心律失常消融;35例中的32例(91%)在无需冠状动脉造影的情况下使用ICE和三维标测进行了消融。35例患者中的29例(83%)实现了急性消融成功。在所有病例中,通过ICE可直接看到导管尖端距离冠状动脉口>1厘米。最早室性心律失常的起源部位为左冠瓣(35例中的17例[49%])、右冠瓣(35例中的9例[26%])、右-左冠瓣交界处(35例中的8例[23%])或右-无冠瓣交界处(35例中的1例[3%])。没有急性或30天时发生冠状动脉损伤、栓塞性卒中、主动脉根部穿孔、主动脉瓣反流恶化或死亡的病例。
在大多数情况下,使用ICE和电解剖标测可安全地对起源于主动脉根部的室性心律失常进行射频消融,无需冠状动脉造影。