Nguyen Minh B, Ceresnak Scott R, Janson Christopher M, Fishberger Steven B, Love Barry A, Blaufox Andrew D, Motonaga Kara S, Dubin Anne M, Nappo Lynn, Pass Robert H
The Children's Hospital at Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, USA.
Pacing Clin Electrophysiol. 2017 Jul;40(7):798-802. doi: 10.1111/pace.13126. Epub 2017 Jun 30.
Ablation within the aortic cusp is safe and effective in adults. There are little data on aortic cusp ablation in the pediatric literature. We investigated the safety and efficacy of aortic cusp ablation in young patients.
A retrospective, descriptive study of aortic cusp ablation in five pediatric electrophysiology centers from 2008 to 2014 was performed. All patients <21 years of age who underwent ablation in the aortic cusps were included. Factors analyzed included patient demographics, procedural details, outcomes, and complications.
Thirteen patients met inclusion criteria (median age 16 years [range 10-20.5] and median body surface area 1.58 m [range 1.12-2.33]). Substrates for ablation included: nine premature ventricular contractions or sustained ventricular tachycardia (69%), two concealed anteroseptal accessory pathways (APs) (15%), one Wolff-Parkinson-White with an anteroseptal AP (8%), and one ectopic atrial tachycardia (8%). Three-dimensional electroanatomic mapping in combination with fluoroscopy was used in 12/13 (92%) patients. Standard 4-mm-tip radiofrequency (RF) current was used in 11/13 (85%) and low-power irrigated-tip RF in 2/13 (15%). Angiography was used in 13/13 and intracardiac echocardiography was additionally utilized in 3/13 (23%). Ablation locations included: eight noncoronary (62%), three left (23%), and two right (15%) cusps. Ablation was acutely successful in all patients. At median follow-up of 20 months, there was one recurrence of PVCs (8%). There were no ablation-related complications and no valvular injuries observed.
Arrhythmias originating from the coronary cusps in this series were successfully and safely ablated in young people without injury to the coronary arteries or the aortic valve.
在成人中,主动脉瓣叶内消融是安全有效的。儿科文献中关于主动脉瓣叶消融的数据很少。我们研究了年轻患者主动脉瓣叶消融的安全性和有效性。
对2008年至2014年在五个儿科电生理中心进行的主动脉瓣叶消融进行回顾性描述性研究。纳入所有年龄小于21岁且在主动脉瓣叶进行消融的患者。分析的因素包括患者人口统计学、手术细节、结果和并发症。
13例患者符合纳入标准(中位年龄16岁[范围10 - 20.5岁],中位体表面积1.58平方米[范围1.12 - 2.33平方米])。消融的基质包括:9例室性早搏或持续性室性心动过速(69%),2例隐匿性前间隔旁道(APs)(15%),1例伴有前间隔AP的预激综合征(8%),以及1例异位房性心动过速(8%)。12/13(92%)例患者使用了三维电解剖标测结合透视。11/13(85%)例患者使用标准4毫米尖端射频(RF)电流,2/13(15%)例患者使用低功率灌注尖端RF。13/13例患者进行了血管造影,3/13(23%)例患者额外使用了心内超声心动图。消融部位包括:8例无冠瓣(62%),3例左冠瓣(23%),2例右冠瓣(15%)。所有患者消融即刻成功。中位随访20个月时,有1例室性早搏复发(8%)。未观察到与消融相关的并发症和瓣膜损伤。
在本系列中,起源于冠状动脉瓣叶的心律失常在年轻人中成功且安全地消融,未损伤冠状动脉或主动脉瓣。