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水溶性联二萘基树枝状大分子的合成及光学性质

Synthesis and optical properties of water-soluble biperylene-based dendrimers.

作者信息

Shao Pin, Jia Ningyang, Zhang Shaojuan, Bai Mingfeng

机构信息

Molecular Imaging Laboratory, Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15219, USA.

出版信息

Chem Commun (Camb). 2014 May 30;50(42):5648-51. doi: 10.1039/c4cc01742k.

Abstract

We report the synthesis and photophysical properties of three biperylene-based dendrimers, which show red fluorescence in water. A fluorescence microscopy study demonstrated uptake of biperylene-based dendrimers in living cells. Our results indicate that these biperylene-based dendrimers are promising candidates in fluorescence imaging applications with the potential as therapeutic carriers.

摘要

我们报道了三种基于联二萘的树枝状大分子的合成及其光物理性质,它们在水中呈现红色荧光。荧光显微镜研究表明基于联二萘的树枝状大分子可被活细胞摄取。我们的结果表明,这些基于联二萘的树枝状大分子在荧光成像应用中是很有前景的候选物,具有作为治疗载体的潜力。

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