Jamal Nausheen, Mundi Jagmeet, Chhetri Dinesh K
Am J Otolaryngol. 2014 Mar-Apr;35(2):159-63. doi: 10.1016/j.amjoto.2013.09.002.
To review our clinical experience with percutaneous injection laryngoplasty at a single institution over a three-year period, and to specifically assess the rate of unintentional injection into the superficial lamina propria (SLP) and compare with results found in the literature.
Medical records were retrospectively reviewed to identify patients who underwent office-based injection laryngoplasty (OBIL) over a three-year period. Video documentation and the written notes of the procedures were reviewed to determine the rate of inadvertent placement of injectate into the SLP. A literature review was performed to identify other reports of this complication and contributing factors.
113 consecutive patients were identified who underwent OBIL in the study period. Of these, 100 patients had adequate records and follow-up available for this review. All patients underwent injection augmentation with bovine collagen using a percutaneous trans-membrane or trans-cartilaginous technique. 96 had improvement in their vocal quality and/or effort. Four patients, who were all women, had unintentional injection into the SLP with resultant no change in voice or worsened voice. All superficially placed injectates were managed conservatively.
Injection into the SLP is a well-recognized possible complication of OBIL. Our results suggest that this complication occurs more often in women than in men, perhaps due to differing laryngeal anatomy and size.
回顾我们在一家机构三年内经皮注射喉成形术的临床经验，并特别评估意外注入浅层固有层（SLP）的发生率，并与文献中的结果进行比较。
对病历进行回顾性分析，以确定在三年期间接受门诊注射喉成形术（OBIL）的患者。回顾手术的视频记录和书面记录，以确定注射剂意外注入SLP的发生率。进行文献综述，以确定关于该并发症及其相关因素的其他报告。
在研究期间，共确定113例连续接受OBIL的患者。其中，100例患者有足够的记录和随访资料可供本次综述。所有患者均采用经皮跨膜或经软骨技术，用牛胶原蛋白进行注射填充。96例患者的嗓音质量和/或发声努力得到改善。4例患者均为女性，意外将注射剂注入SLP，导致嗓音无变化或嗓音恶化。所有浅表注射均采用保守治疗。
注入SLP是OBIL一种公认的可能并发症。我们的结果表明，这种并发症在女性中比在男性中更常见，可能是由于喉的解剖结构和大小不同。
