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[医护人员面临的生物风险]

[Biological risk among health workers].

作者信息

Caciari Tiziana, Casale Teodorico, Tomei Gianfranco, Capozzella Assunta, Trovè Lorenzo, Lepanto Rosa, Pimpinella Benedetta, Di Pastena Claudia, Scala Barbara, De Sio Simone, Tomei Francesco, Rosati Maria Valeria

出版信息

G Ital Med Lav Ergon. 2013 Jul-Sep;35(3):163-7.

Abstract

INTRODUCTION

In health care the contact with body fluids, such as saliva or blood is frequent. The aim of our study was to analyze whether the exposure to biological risks in health care, in particular exposure to HBV and HCV, could cause alterations of some liver parameters.

MATERIALS AND METHODS

Our study analyzes of 254 health care workers of a big hospital in Rome. The subjects exposed to biological risks were divided into two groups, one exposed to a high biological risk and the other one exposed to a low biological risk, according to individual duties and/or the departments where they carry out their work. We checked the markers for hepatitis B and C in order to highlight a possible infection, the possible vaccine coverage and the control of the antibody titer by previous infection. We measured the values of transaminases, GGT, alkaline phosphatase, total bilirubin and fractional proteinaemia total and electrophoresis.

RESULTS

In health care workers exposed to high risk the average values of transaminases, total protein, alkaline phosphatase, gamma GT, total bilirubin were not significant compared to the some values formed in workers exposed to low risk (p > 0.05). Subjects positive for hepatitis B and C were 4% in the group of workers exposed to high risk (class 1) while in the group of workers exposed to low risk (class 2) the percentage of exposed individuals was 0.01% for the hepatitis B and 2.6% for hepatitis C.

DISCUSSION AND CONCLUSIONS

We found a small numbers of positive cases of hepatitis B and C in people exposed to biological agents. We did not find alterations of the average values of transaminases, total protein, alkaline phosphatase, gamma GT, total bilirubin and albumin in positive cases, so that we can say that the proper use of personal protective equipment, training and information of workers and the observance of universal precautions are effective in protecting workers.

摘要

引言

在医疗保健领域,与唾液或血液等体液的接触十分频繁。我们研究的目的是分析医疗保健中的生物风险暴露,尤其是接触乙肝病毒和丙肝病毒,是否会导致某些肝脏参数的改变。

材料与方法

我们对罗马一家大型医院的254名医护人员进行了研究分析。根据个人职责和/或工作所在部门,将面临生物风险的受试者分为两组,一组面临高生物风险,另一组面临低生物风险。我们检查了乙肝和丙肝标志物,以突出可能的感染情况、可能的疫苗接种覆盖率以及既往感染对抗体滴度的控制情况。我们测量了转氨酶、γ-谷氨酰转移酶(GGT)、碱性磷酸酶、总胆红素以及总蛋白和蛋白电泳分数的值。

结果

与低风险暴露的工作人员所形成的某些值相比,高风险暴露的医护人员的转氨酶、总蛋白、碱性磷酸酶、γ-谷氨酰转移酶、总胆红素的平均值并无显著差异(p>0.05)。在高风险暴露组(1级)的工作人员中,乙肝和丙肝呈阳性的受试者为4%,而在低风险暴露组(2级)的工作人员中,乙肝暴露个体的百分比为0.01%,丙肝为2.6%。

讨论与结论

我们发现接触生物制剂的人群中乙肝和丙肝阳性病例数量较少。我们未在阳性病例中发现转氨酶、总蛋白、碱性磷酸酶、γ-谷氨酰转移酶、总胆红素和白蛋白平均值的改变,因此可以说正确使用个人防护设备、对工作人员进行培训和提供信息以及遵守通用预防措施对保护工作人员是有效的。

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