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生酮饮食疗法对伴有难治性癫痫的脑炎有效。

Ketogenic diet therapy is effective in encephalitis with refractory seizures.

作者信息

Matsuzono Kosuke, Kurata Tomoko, Deguchi Shoko, Yamashita Toru, Deguchi Kentaro, Abe Koji

出版信息

Neurol Res. 2014 Oct;36(10):906-10. doi: 10.1179/1743132814Y.0000000371. Epub 2014 Apr 16.

Abstract

OBJECTIVE AND IMPORTANCE

Although ketogenic diet therapy is effective in refractory seizures in childhood, its effect on adult encephalitis with similar refractory seizures and prolonged encephalopathy has not been well reported.

CLINICAL PRESENTATION

We report here a case of a 22-year-old man with acute encephalitis with refractory repetitive partial seizures (AERRPS).

INTERVENTION

Partial seizures of the face developed to repeated generalized convulsions, which were refractory against anti-epileptic drugs and a high dose of propofol. After struggling for 9 months, he dramatically recovered after ketogenic diet therapy.

CONCLUSION

Ketogenic diet therapy may be an important tool to help cure AERRPS.

摘要

目的及重要性

尽管生酮饮食疗法对儿童难治性癫痫有效,但其对伴有类似难治性癫痫及长期脑病的成人脑炎的影响尚未得到充分报道。

临床表现

我们在此报告一例22岁男性急性脑炎伴难治性重复性部分性癫痫发作(AERRPS)的病例。

干预措施

面部部分性癫痫发作发展为反复全身性惊厥,对抗癫痫药物及高剂量丙泊酚均无效。经过9个月的艰难治疗,他在接受生酮饮食疗法后显著康复。

结论

生酮饮食疗法可能是帮助治愈AERRPS的一项重要手段。

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