• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

生酮饮食疗法对伴有难治性癫痫的脑炎有效。

Ketogenic diet therapy is effective in encephalitis with refractory seizures.

作者信息

Matsuzono Kosuke, Kurata Tomoko, Deguchi Shoko, Yamashita Toru, Deguchi Kentaro, Abe Koji

出版信息

Neurol Res. 2014 Oct;36(10):906-10. doi: 10.1179/1743132814Y.0000000371. Epub 2014 Apr 16.

DOI:10.1179/1743132814Y.0000000371
PMID:24735348
Abstract

OBJECTIVE AND IMPORTANCE

Although ketogenic diet therapy is effective in refractory seizures in childhood, its effect on adult encephalitis with similar refractory seizures and prolonged encephalopathy has not been well reported.

CLINICAL PRESENTATION

We report here a case of a 22-year-old man with acute encephalitis with refractory repetitive partial seizures (AERRPS).

INTERVENTION

Partial seizures of the face developed to repeated generalized convulsions, which were refractory against anti-epileptic drugs and a high dose of propofol. After struggling for 9 months, he dramatically recovered after ketogenic diet therapy.

CONCLUSION

Ketogenic diet therapy may be an important tool to help cure AERRPS.

摘要

目的及重要性

尽管生酮饮食疗法对儿童难治性癫痫有效，但其对伴有类似难治性癫痫及长期脑病的成人脑炎的影响尚未得到充分报道。

临床表现

我们在此报告一例22岁男性急性脑炎伴难治性重复性部分性癫痫发作（AERRPS）的病例。

干预措施

面部部分性癫痫发作发展为反复全身性惊厥，对抗癫痫药物及高剂量丙泊酚均无效。经过9个月的艰难治疗，他在接受生酮饮食疗法后显著康复。

结论

生酮饮食疗法可能是帮助治愈AERRPS的一项重要手段。

相似文献

1
Ketogenic diet therapy is effective in encephalitis with refractory seizures.生酮饮食疗法对伴有难治性癫痫的脑炎有效。
Neurol Res. 2014 Oct;36(10):906-10. doi: 10.1179/1743132814Y.0000000371. Epub 2014 Apr 16.
2
Acute encephalitis with refractory, repetitive partial seizures: Pathological findings and a new therapeutic approach using tacrolimus.伴有难治性、反复部分性癫痫发作的急性脑炎：病理 findings 及使用他克莫司的一种新治疗方法
Brain Dev. 2016 Sep;38(8):772-6. doi: 10.1016/j.braindev.2016.02.006. Epub 2016 Feb 20.
3
Ketogenic diet efficacy in the treatment of intractable epileptic spasms.生酮饮食治疗耐药性癫痫痉挛的疗效。
Pediatr Neurol. 2014 Mar;50(3):224-7. doi: 10.1016/j.pediatrneurol.2013.11.021. Epub 2013 Dec 4.
4
Acute encephalitis with refractory, repetitive partial seizures: case reports of this unusual post-encephalitic epilepsy.伴有难治性、反复性部分性癫痫发作的急性脑炎：这种不寻常的脑炎后癫痫的病例报告
Brain Dev. 2007 Apr;29(3):147-56. doi: 10.1016/j.braindev.2006.08.005. Epub 2006 Sep 27.
5
Acute encephalitis with refractory, repetitive partial seizures (AERRPS): a peculiar form of childhood encephalitis.伴有难治性、反复部分性发作的急性脑炎（AERRPS）：一种儿童脑炎的特殊形式。
Acta Neurol Scand. 2010 Apr;121(4):251-6. doi: 10.1111/j.1600-0404.2009.01198.x. Epub 2009 Dec 17.
6
[A case of non-herpetic acute limbic encephalitis in childhood--comparison with acute encephalitis with refractory repetitive partial seizures (AERRPS)].
No To Hattatsu. 2007 May;39(3):221-5.
7
A case of acute encephalitis with refractory, repetitive partial seizures, presenting autoantibody to glutamate receptor Gluepsilon2.一例急性脑炎伴难治性、重复性部分性癫痫发作，呈现针对谷氨酸受体Gluε2的自身抗体。
Brain Dev. 2005 Oct;27(7):531-4. doi: 10.1016/j.braindev.2004.12.005.
8
Can an early 24-hour EEG predict the response to the ketogenic diet? A prospective study in 34 children and adults with refractory epilepsy treated with the ketogenic diet.早期24小时脑电图能否预测生酮饮食的反应？一项对34例接受生酮饮食治疗的难治性癫痫儿童和成人的前瞻性研究。
Seizure. 2014 Jun;23(6):468-74. doi: 10.1016/j.seizure.2014.03.008. Epub 2014 Apr 2.
9
Acute encephalitis with refractory, repetitive partial seizures.
Brain Dev. 2008 May;30(5):356-61. doi: 10.1016/j.braindev.2007.10.008. Epub 2007 Dec 19.
10
High-dose phenobarbital with intermittent short-acting barbiturates for acute encephalitis with refractory, repetitive partial seizures.大剂量苯巴比妥联合间歇性短效巴比妥类药物治疗伴有难治性、反复部分性发作的急性脑炎。
Pediatr Int. 2016 Aug;58(8):750-3. doi: 10.1111/ped.12934. Epub 2016 Jun 8.

引用本文的文献

1
Ketogenic diet for super-refractory status epilepticus (SRSE) with NORSE and FIRES: Single tertiary center experience and literature data.生酮饮食治疗伴有暴发性难治性癫痫性脑病（NORSE）和发热感染相关癫痫综合征（FIRES）的超级难治性癫痫持续状态（SRSE）：单一三级中心经验及文献数据
Front Neurol. 2023 Apr 13;14:1134827. doi: 10.3389/fneur.2023.1134827. eCollection 2023.
2
Seizure burden and neuropsychological outcomes of new-onset refractory status epilepticus: Systematic review.新发难治性癫痫持续状态的发作负担及神经心理学结局：系统评价
Front Neurol. 2023 Jan 24;14:1095061. doi: 10.3389/fneur.2023.1095061. eCollection 2023.
3
Ketogenic Diet Therapy for the Treatment of Post-encephalitic and Autoimmune-Associated Epilepsies.
生酮饮食疗法用于治疗脑炎后和自身免疫相关性癫痫
Front Neurol. 2021 Jun 16;12:624202. doi: 10.3389/fneur.2021.624202. eCollection 2021.
4
Ketogenic Diet Therapies for Seizures and Status Epilepticus.生酮饮食疗法治疗癫痫发作和癫痫持续状态。
Semin Neurol. 2020 Dec;40(6):719-729. doi: 10.1055/s-0040-1719077. Epub 2020 Nov 5.
5
Systematic review of ketogenic diet use in adult patients with status epilepticus.成人癫痫持续状态患者使用生酮饮食的系统评价。
Epilepsia Open. 2019 Nov 24;5(1):10-21. doi: 10.1002/epi4.12370. eCollection 2020 Mar.
6
Acute encephalitis with refractory, repetitive partial seizures: A case report and literature review.伴有难治性反复部分性癫痫发作的急性脑炎：一例报告及文献综述
Exp Ther Med. 2016 Nov;12(5):3401-3404. doi: 10.3892/etm.2016.3750. Epub 2016 Sep 27.