Williams Keith L, Gooley Andrew A, Wilkins Marc R, Packer Nicolle H
BKG Group, 2B Mosman St, Mosman, NSW 2088, Australia.
TRAJAN Scientific & Medical, 7 Argent Place, Ringwood, Victoria 3134, Australia.
J Proteomics. 2014 Jul 31;107:13-23. doi: 10.1016/j.jprot.2014.04.006. Epub 2014 Apr 13.
This is the story of the experience of a multidisciplinary group at Macquarie University in Sydney as we participated in, and impacted upon, major currents that washed through protein science as the field of Proteomics emerged. The large scale analysis of proteins became possible. This is not a history of the field. Instead we have tried to encapsulate the stimulating personal ride we had transiting from conventional academe, to a Major National Research Facility, to the formation of Proteomics company Proteome Systems Ltd. There were lots of blind alleys, wrong directions, but we also got some things right and our efforts, along with those of many other groups around the world, did change the face of protein science. While the transformation is by no means yet complete, protein science is very different from the field in the 1990s. This article is part of a Special Issue entitled: 20years of Proteomics in memory of Viatliano Pallini. Guest Editors: Luca Bini, Juan J. Calvete, Natacha Turck, Denis Hochstrasser and Jean-Charles Sanchez.
这是悉尼麦考瑞大学一个多学科团队的经历故事，当时随着蛋白质组学领域的兴起，我们参与并影响了席卷蛋白质科学的主要潮流。蛋白质的大规模分析成为可能。这不是该领域的历史。相反，我们试图概括我们从传统学术界，到一个国家重大研究设施，再到成立蛋白质组学公司Proteome Systems Ltd. 所经历的激动人心的个人历程。途中有许多死胡同和错误方向，但我们也做对了一些事情，而且我们的努力，连同世界上许多其他团队的努力，确实改变了蛋白质科学的面貌。虽然这种转变远未完成，但蛋白质科学与20世纪90年代的该领域已大不相同。本文是名为《纪念维亚特利亚诺·帕利尼的蛋白质组学20年》特刊的一部分。客座编辑：卢卡·比尼、胡安·J·卡尔韦特、娜塔莎·图尔克、丹尼斯·霍施特拉瑟和让 - 查尔斯·桑切斯。
