Wang Yanjie, Yang Xin, Li Xiaodong, He Xiaojing, Zhao Yang
From the 1Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, China; and 2Department of Obstetrics and Gynecology, The Second Hospital of Hebei Medical University, Hebei Province, China.
Menopause. 2014 Nov;21(11):1190-6. doi: 10.1097/GME.0000000000000233.
Obstetrician-gynecologists' (ob-gyns) knowledge of the benefits and risks of-and attitude toward-menopausal hormone therapy (HT) have evolved since the publication of the Heart and Estrogen/progestin Replacement Study and the Women's Health Initiative. The survey investigated Chinese ob-gyns' perception and personal use of-and attitude toward-HT.
A total of 2,000 self-administered questionnaires were sent to female ob-gyns who attended gynecological endocrinology workshops in 15 provinces and cities in China from February to May 2013.
A total of 904 eligible questionnaires were collected (response rate, 45.2%). Most of the respondents knew that HT could relieve menopausal symptoms (97.7%) and prevent osteoporosis (93.5%). Most (69.4%) of the respondents thought that HT would increase the risk of breast cancer, and 52.9% thought that HT would increase the risk of endometrial cancer. The most common concern regarding adverse effects of HT was risk of breast cancer, followed by risk of endometrial cancer, risk of venous thrombosis, and weight gain. One hundred twenty-three of 324 symptomatic respondents (38.0%) reported HT use, and a further 28 respondents (8.6%) had tried transdermal and vaginal estrogen creams.
These findings show better knowledge of HT among Chinese ob-gyns compared with the general Chinese population. However, HT use is relatively low, and ob-gyns seem to be overconcerned with the risks of HT. HT education must be promoted among Chinese ob-gyns to enhance the proper use of HT in the general population.
自《心脏与雌激素/孕激素替代研究》及《妇女健康倡议》发表以来，妇产科医生对绝经激素治疗（HT）的益处、风险及态度已有所演变。本调查旨在研究中国妇产科医生对HT的认知、个人使用情况及态度。
2013年2月至5月，共向中国15个省市参加妇科内分泌学研讨会的女性妇产科医生发放了2000份自填式问卷。
共收集到904份有效问卷（回复率为45.2%）。大多数受访者知道HT可缓解绝经症状（97.7%）及预防骨质疏松症（93.5%）。大多数受访者（69.4%）认为HT会增加患乳腺癌的风险，52.9%的受访者认为HT会增加患子宫内膜癌的风险。对HT不良反应最常见的担忧是患乳腺癌的风险，其次是患子宫内膜癌的风险、静脉血栓形成风险及体重增加。324名有症状的受访者中有123人（38.0%）报告使用过HT，另有28名受访者（8.6%）曾尝试过经皮和阴道雌激素乳膏。
这些研究结果表明，与中国普通人群相比，中国妇产科医生对HT的了解更多。然而，HT的使用率相对较低，且妇产科医生似乎对HT的风险过度担忧。必须在中国妇产科医生中加强HT教育，以促进HT在普通人群中的合理使用。
