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[下丘脑内注射P物质期间大鼠的视觉诱发电位与禁水]

[Visual evoked potentials and water deprivation of rats during intrahypothalamic application of substance P].

作者信息

Kolle U, Bartsch P

机构信息

Neurophysiologische Abteilung, Bereich Medizin (Charité), Humboldt-Universität, Berlin, DDR.

出版信息

Biomed Biochim Acta. 1988;47(12):1065-71.

PMID:2473740
Abstract

Visually evoked potentials (VEP) were recorded in the visual cortex, the dorsal geniculate nucleus and the lateral hypothalamus of satiated and water-deprived rats with and without additional drinking sounds to strengthen motivation and were compared with those during substance-P-injections. Differences in VEP and corresponding spatial and temporal interrelationships of these areas were found by using the method of coincidence of single VEP. Variations of drinking behaviour, weight loss and motor activity were recorded. The findings are discussed with regard to SP and its function as a "regulid peptide".

摘要

在饱足和缺水的大鼠的视觉皮层、背侧膝状核和外侧下丘脑记录视觉诱发电位(VEP),有无额外的饮水声音以增强动机,并与注射P物质期间的情况进行比较。通过使用单个VEP的重合方法,发现了这些区域VEP的差异以及相应的空间和时间相互关系。记录了饮水行为、体重减轻和运动活动的变化。结合P物质及其作为“调节肽”的功能对这些发现进行了讨论。

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