Plech Agata R, Herba Ewa, Pojda-Wilczek Dorota, Makowiecka-Obidzińska Katarzyna, Pojda Stefan M, Plech Andrzej
Katedry i Oddziału Klinicznego Okulistyki w Bytomiu Slaskiej Akademii Medycznej w Katowicach.
Klin Oczna. 2006;108(4-6):155-8.
Numerous neurotransmitters and neuromodulators operating on all levels of the visual system, influence the parameters of cortical evoked response. The aim of this study was to find the influence of dopamine (DA) injected into the lateral geniculate body (nucleus) on flash visual evoked response (FVEP).
The experiments were performed on adult Wistar rats. They were implanted with 1 caniula conducted into the lateral geniculate body and 2 electrodes: active under the skull on dura mater in occipital region of brain and reference one on the skull in the interorbital region. FVEPs curve before and after injection into the lateral geniculate body 0.9% NaCl and DA were analyzed.
DA in the lateral geniculate body causes increasing latency and amplitude of FVEP peaks.
Dopamine in the lateral geniculate body can improve visual perception in the occipital cortex.
众多作用于视觉系统各级水平的神经递质和神经调质会影响皮质诱发反应的参数。本研究的目的是探究注入外侧膝状体（核）的多巴胺（DA）对闪光视觉诱发电位（FVEP）的影响。
实验在成年Wistar大鼠身上进行。将一根导管植入外侧膝状体，并植入两个电极：一个置于脑枕叶区域硬脑膜下颅骨下方作为活动电极，另一个置于眶间区域颅骨上作为参考电极。分析向外侧膝状体注射0.9%氯化钠溶液和多巴胺前后的FVEP曲线。
外侧膝状体中的多巴胺会导致FVEP峰潜伏期延长和波幅增大。
外侧膝状体中的多巴胺可改善枕叶皮质的视觉感知。
