Department of Medicine, Division of Gastroenterology and Hepatology, Penn State University Milton S. Hershey Medical Center, Hershey, Pennsylvania.
Cancer. 2014 Jul 15;120(14):2106-13. doi: 10.1002/cncr.28707. Epub 2014 Apr 15.
There is limited information about colorectal cancer (CRC) screening trends in high-risk groups, including the black, obese, diabetic, and smoking populations. For this study, the authors evaluated national CRC screening trends in these high-risk groups to provide insights into whether screening resources are being appropriately used.
This was a nationally representative, population-based study using the Behavioral Risk Factor Surveillance System from the Centers for Disease Control. Data analysis was performed using bivariate analyses with weighted logistic regression.
In the general population, CRC screening increased significantly from 59% to 65% during the years 2006 to 2010. The screening prevalence in non-Hispanic blacks was 58% in 2006 and 65% in 2010. Among obese individuals, the prevalence of up-to-date CRC screening increased significantly from 59% in 2006 to 66% in 2010. Screening prevalence in individuals with diabetes was 63% in 2006 and 69% in 2010. The CRC screening prevalence in current smokers was 45% in 2006 and 50% in 2010. The odds of CRC screening in the non-Hispanic black population, the obese population, and the diabetic population were higher than in non-Hispanic whites, normal weight individuals, and the population without diabetes, respectively. Current smokers had significantly lower odds of CRC screening than never-smokers in the years studied (2006: odds ratio [OR], 0.71; 95% confidence interval [CI], 0.66-0.76; 2008: OR, 0.67; 95% CI, 0.63-0.71; 2010: OR, 0.69; 95% CI, 0.66-0.73).
The prevalence of CRC screening in high-risk groups is trending upward. Despite this, current smokers have significantly lower odds of CRC screening compared with the general population.
关于高危人群（包括黑人、肥胖人群、糖尿病患者和吸烟者）的结直肠癌（CRC）筛查趋势，目前信息有限。本研究评估了这些高危人群的全国 CRC 筛查趋势，以了解是否适当利用了筛查资源。
这是一项基于人群的全国代表性研究，使用了疾病控制中心的行为风险因素监测系统。数据分析采用了双变量分析和加权逻辑回归。
在一般人群中，CRC 筛查率从 2006 年至 2010 年从 59%显著上升至 65%。2006 年非西班牙裔黑人的筛查率为 58%，2010 年为 65%。在肥胖人群中，最新 CRC 筛查的流行率从 2006 年的 59%显著上升至 2010 年的 66%。2006 年糖尿病患者的筛查率为 63%，2010 年为 69%。当前吸烟者的 CRC 筛查率在 2006 年为 45%，2010 年为 50%。非西班牙裔黑人、肥胖人群和糖尿病患者的 CRC 筛查几率均高于非西班牙裔白人、体重正常人群和无糖尿病人群。在研究期间（2006 年：比值比[OR]，0.71；95%置信区间[CI]，0.66-0.76；2008 年：OR，0.67；95% CI，0.63-0.71；2010 年：OR，0.69；95% CI，0.66-0.73），与一般人群相比，当前吸烟者的 CRC 筛查几率显著降低。
高危人群的 CRC 筛查率呈上升趋势。尽管如此，与一般人群相比，当前吸烟者的 CRC 筛查几率显著降低。
