Jakubovic Baruch D, Yan Andrew T, Wald Ron
Semin Dial. 2014 Mar;27(2):179-87. doi: 10.1111/sdi.12184.
Dialysis intensification from conventional regimens (typically thrice weekly, 4 hours per session) is increasingly utilized with the intent of improving the cardiovascular health and quality of life of chronic dialysis recipients. While home nocturnal hemodialysis offers the opportunity for maximal intensification of dialysis, it is inaccessible to the majority of dialysis recipients who are unable to self-administer hemodialysis in their own homes. In-center nocturnal hemodialysis (INHD) permits the intensification of conventional hemodialysis with the benefits of nursing support and supervision in addition to freedom from dialysis during productive daytime hours. Although no randomized trials have evaluated the relative merits of INHD, preliminary data indicate that INHD is a viable option that may confer a variety of benefits for chronic dialysis recipients.
从传统方案(通常每周三次,每次4小时)强化透析越来越多地被采用,目的是改善慢性透析患者的心血管健康和生活质量。虽然家庭夜间血液透析提供了最大程度强化透析的机会,但大多数无法在家自行进行血液透析的透析患者无法使用。中心夜间血液透析(INHD)在提供护理支持和监督的同时,还能让患者在白天工作时间免于透析,从而实现传统血液透析的强化。尽管尚无随机试验评估INHD的相对优势,但初步数据表明,INHD是一个可行的选择,可能为慢性透析患者带来多种益处。