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医疗保险药物治疗管理(MTM)项目的影响:评估临床和经济结果。

Impact of a Medicare MTM program: evaluating clinical and economic outcomes.

作者信息

Hui Rita L, Yamada Brian D, Spence Michele M, Jeong Erwin W, Chan James

机构信息

1800 Harrison St, Ste 1301, Oakland, CA 94612. E-mail:

出版信息

Am J Manag Care. 2014 Feb 1;20(2):e43-51.

Abstract

OBJECTIVES

To assess the impact of a Medicare Medication Therapy Management (MTM) program in a large integrated health plan on patient mortality, hospitalization and emergency department (ED) utilization, and daily prescription costs.

STUDY DESIGN

Retrospective matched cohort study.

METHODS

Patients who received MTM services between 2006 and 2010 were matched to control patients who were enrolled in Medicare but did not receive MTM services. They were matched in a 1:4 ratio based on age, gender, geographic location, and prospective diagnostic-cost-group (DxCG) risk score. Multivariate regressions were used to analyze the outcomes. Subgroup analyses were conducted for patients enrolled in 2010 because the Centers for Medicare & Medicaid Services lowered the drug-cost threshold for MTM eligibility and changed from opt-in to optout participation.

RESULTS

We identified 34,532 members who received MTM services and 138,128 control members. The MTM group was found to have a significantly reduced mortality (hazard ratio 0.86, 95% confidence interval [CI], 0.84-0.88; P <.001), lower odds for hospitalization (odds ratio [OR] = 0.97, 95% CI, 0.94-0.99; P = .018), higher odds for emergency department visits (OR = 1.17, 95% CI, 1.14-1.20; P <.001), and no differences in change in daily medication costs when compared to the matched group. The subgroup analysis of the 2010 cohort found similar results with better outcomes than the overall cohort.

CONCLUSIONS

Medicare MTM services resulted in lower mortality and odds for hospitalization for enrolled patients compared with matched controls. This study observed an increase in ED visits and no differences in change in daily medication costs in MTM services.

摘要

目的

评估大型综合健康计划中的医疗保险药物治疗管理(MTM)项目对患者死亡率、住院率、急诊科(ED)利用率及每日处方费用的影响。

研究设计

回顾性匹配队列研究。

方法

将2006年至2010年间接受MTM服务的患者与参加医疗保险但未接受MTM服务的对照患者进行匹配。根据年龄、性别、地理位置和前瞻性诊断成本组(DxCG)风险评分,以1:4的比例进行匹配。采用多变量回归分析结果。对2010年入组的患者进行亚组分析,因为医疗保险和医疗补助服务中心降低了MTM资格的药物成本门槛,并从选择加入改为选择退出参与方式。

结果

我们确定了34532名接受MTM服务的成员和138128名对照成员。发现MTM组的死亡率显著降低(风险比0.86,95%置信区间[CI],0.84 - 0.88;P <.001),住院几率较低(优势比[OR] = 0.97,95% CI,0.94 - 0.99;P = 0.018),急诊科就诊几率较高(OR = 1.17,95% CI,1.14 - 1.20;P <.001),与匹配组相比,每日药物成本变化无差异。2010年队列的亚组分析发现了类似结果,且结果优于总体队列。

结论

与匹配的对照组相比,医疗保险MTM服务使入组患者的死亡率和住院几率降低。本研究观察到MTM服务中急诊科就诊次数增加,且每日药物成本变化无差异。

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