J Health Care Poor Underserved. 2023;34(1):192-207. doi: 10.1353/hpu.2023.0013.
This study examined how patients take complex medication regimens at home. Participants were primary care patients, 21 years or older, and prescribed three or more medications. Interviews assessed medication dosing schedules, medication knowledge, and dosing errors. Participants (N=441) were middle aged (mean 56.9); the majority were Hispanic/Latino (73.4%), had limited English proficiency (59.0%), and had limited health literacy (89.0%). One in five participants dosed medication five or more times per day, although no participants in the sample had a label instructing them to take medication more than times times daily. On average, participants correctly identified the purpose of 65% of their medications. Half of participants made one or more dosing errors. Less than high school education and a regimen size of six or more medications were independently associated with less medication knowledge, whereas language discordant label instructions were associated with dosing errors. Screening for regimen dosing complication and interventions to simplify dosing schedules are needed.
本研究考察了患者如何在家中服用复杂的药物治疗方案。参与者为初级保健患者，年龄在 21 岁及以上，开了三种或更多种药物。访谈评估了药物剂量方案、药物知识和剂量错误。参与者（N=441）年龄在中年（平均 56.9 岁）；大多数是西班牙裔/拉丁裔（73.4%），英语水平有限（59.0%），健康素养有限（89.0%）。尽管样本中没有参与者的标签指示他们每天服用药物超过一次，但五分之一的参与者每天服药五次或更多次。平均而言，参与者正确识别了 65%的药物的用途。一半的参与者出现了一次或多次剂量错误。受教育程度低于高中和治疗方案规模为六种或更多药物与药物知识较少有关，而语言不一致的标签说明与剂量错误有关。需要对治疗方案剂量并发症进行筛查，并采取措施简化剂量方案。
