The authors' affiliations are listed in the Appendix.
N Engl J Med. 2014 Oct 9;371(15):1418-25. doi: 10.1056/NEJMoa1404505. Epub 2014 Apr 16.
In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Full-length genome sequencing and phylogenetic analysis showed that EBOV from Guinea forms a separate clade in relationship to the known EBOV strains from the Democratic Republic of Congo and Gabon. Epidemiologic investigation linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December 2013. This study demonstrates the emergence of a new EBOV strain in Guinea.
2014 年 3 月，世界卫生组织接到通知，在几内亚暴发了一种传染病，其特征是发热、严重腹泻、呕吐和高死亡率。病毒学调查确定扎伊尔埃博拉病毒（EBOV）是病原体。全长基因组测序和系统发育分析显示，来自几内亚的 EBOV 与来自刚果民主共和国和加蓬的已知 EBOV 株形成一个单独的分支。流行病学调查将实验室确诊病例与 2013 年 12 月暴发的首例推定死亡病例联系起来。本研究表明在几内亚出现了一种新的 EBOV 株。
