Khera Rachna, Uppin Shantveer G, Uppin Megha S, Sundaram Challa
Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India.
Indian J Pathol Microbiol. 2014 Jan-Mar;57(1):105-8. doi: 10.4103/0377-4929.130914.
Clear cell papillary cholangiocarcinoma is a rare variant of intrahepatic cholangiocarcinoma with only nine reported cases in the literature. This tumor needs to be differentiated from clear cell variant of hepatocellular carcinoma and other metastatic clear cell carcinomas. This tumor is known to have better prognosis compared to conventional intrahepatic cholangiocarcinoma. Hence, it is important to correctly diagnose this entity and differentiate it from other histologic mimics. We describe clinical, histopathological, and immunohistochemical findings of one such rare case in a 66-year-old gentleman who was incidentally detected to have an intrahepatic tumor at routine ultrasound examination.A review of all the similar cases reported so far in the literature is also provided.
透明细胞乳头状胆管癌是肝内胆管癌的一种罕见变异类型，文献中仅报道过9例。该肿瘤需要与肝细胞癌的透明细胞变异型及其他转移性透明细胞癌相鉴别。已知该肿瘤与传统肝内胆管癌相比预后较好。因此，正确诊断该实体并将其与其他组织学相似病变区分开来很重要。我们描述了一名66岁男性的此类罕见病例的临床、组织病理学和免疫组化结果，该患者在常规超声检查时偶然发现肝内有肿瘤。本文还对文献中迄今为止报道的所有类似病例进行了综述。
