Terzi Aysen, Uner Aysegul Hasegeli
Department of Pathology, Baskent University, School of Medicine, Bahcelievler, Turkey.
Indian J Pathol Microbiol. 2012 Oct-Dec;55(4):543-5. doi: 10.4103/0377-4929.107809.
Invasive papillary carcinoma is a rare variant of breast cancer. We report an unusual case of invasive papillary carcinoma of the breast with high nuclear grade, brisk mitosis, necrosis, extensive apocrine differentiation, and intense lymphoplasmacytic infiltrate; additionally triple-negativity for estrogen and progesterone receptors and Her2 neu. The patient underwent modified radical mastectomy and adjuvant chemotherapy. But, it was a node negative breast carcinoma. Increasing the awareness of this clinicopathologic entity would be helpful in avoiding overtreatment of patients with this cancer even if the tumor has negative morphological and immunohistochemical prognosticators.
浸润性乳头状癌是乳腺癌的一种罕见变异型。我们报告了一例不寻常的乳腺浸润性乳头状癌病例，其具有高核分级、活跃的有丝分裂、坏死、广泛的大汗腺分化以及密集的淋巴细胞浆细胞浸润；此外，雌激素和孕激素受体及人表皮生长因子受体2（Her2 neu）均为三阴性。该患者接受了改良根治性乳房切除术及辅助化疗。但这是一例无淋巴结转移的乳腺癌。提高对这种临床病理实体的认识将有助于避免对患有这种癌症的患者进行过度治疗，即使肿瘤具有阴性的形态学和免疫组化预后指标。
