Anderson T A, Schick V, Herbenick D, Dodge B, Fortenberry J D
Department of Internal Medicine, Division of Infectious Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Division of Management, Policy, and Community Health, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Sex Transm Infect. 2014 Nov;90(7):529-31. doi: 10.1136/sextrans-2014-051558. Epub 2014 Apr 16.
The objective of the study was to determine the potential of human papillomavirus (HPV) transmission via shared sex toys, and determine whether cleaning practices implemented by the study participants were effective.
Vibrator 1 was composed of thermoplastic elastomer. Vibrator 2 was composed of silicone. Twelve women, recruited from a university, used each vibrator on separate occasions and provided self-collected vaginal and vibrator samples (obtained from the vibrator shaft and handle), collected immediately after use, immediately after cleaning with a commercially available cleaner, and 24 h after cleaning. Vaginal and vibrator samples were assessed for HPV DNA by the Roche Linear Array HPV Genotyping Test.
HPV was detected in the vaginal samples of 9/12 (75%) women. Vibrator 1 shaft swabs were HPV positive before cleaning in 89% (8/9), immediately after cleaning in 56% (5/9), and 24 h after cleaning in 40% (2/5) of those that were HPV positive immediately after cleaning. Vibrator 2 shaft swabs were HPV positive before cleaning in 67% (6/9), immediately after cleaning in 44% (4/9), and 24 h after cleaning in none.
HPV was detected on at least one vibrator immediately after use in the women with vaginal HPV. This supports the potential for HPV transmission via shared sex toy use, and is additionally supported by continued detection of HPV up to 24 h after standard cleaning. The data add to understanding of the range of sexual behaviours associated with HPV transmission, and the need for evidence-based recommendations for sex toy cleaning.
本研究的目的是确定人乳头瘤病毒（HPV）通过共享性玩具传播的可能性，并确定研究参与者实施的清洁措施是否有效。
振动器1由热塑性弹性体制成。振动器2由硅树脂制成。从一所大学招募了12名女性，她们在不同时间使用每个振动器，并提供自我采集的阴道和振动器样本（从振动器轴和手柄获取），分别在使用后、用市售清洁剂清洁后立即以及清洁后24小时采集。通过罗氏线性阵列HPV基因分型检测评估阴道和振动器样本中的HPV DNA。
在12名女性中的9名（75%）阴道样本中检测到HPV。振动器1轴拭子在清洁前HPV阳性率为89%（8/9），清洁后立即为56%（5/9），在清洁后立即HPV阳性的样本中，清洁后24小时为40%（2/5）。振动器2轴拭子在清洁前HPV阳性率为67%（6/9），清洁后立即为44%（4/9），清洁后24小时均未检测到。
在患有阴道HPV的女性使用后立即在至少一个振动器上检测到HPV。这支持了通过共享性玩具使用传播HPV的可能性，并且在标准清洁后长达24小时持续检测到HPV进一步支持了这一点。这些数据有助于理解与HPV传播相关的性行为范围，以及对基于证据的性玩具清洁建议的需求。
