Nguyen Harrison P, Tyring Stephen K
Baylor College of Medicine, Houston, TX, USA; Department of Dermatology, University of Texas Health Science Center at Houston, Houston, TX, USA; Center for Clinical Studies, Houston, TX, USA.
Skin Therapy Lett. 2014 Mar-Apr;19(2):5-8.
Molluscum contagiosum is a poxvirus infection of the skin that is commonly observed in children. The molluscum contagiosum virus (MCV) expresses several gene-products that are involved in its pathogenesis and evasion of the host immune system. MCV can be transmitted both to other sites of the body and to other individuals through direct physical contact as well as fomites. While diagnosis is generally straightforward clinically, management of molluscum contagiosum is controversial. Several treatment options are available for the destruction of individual lesions, but there is insufficient evidence for therapeutic intervention being any more effective than natural, spontaneous resolution. Complex cases, such as infection occurring in immunocompromised patients and in mucocutaneous sites, require an alternative approach to management. Molluscum contagiosum continues to represent a burden on children and parents worldwide.
传染性软疣是一种常见于儿童的皮肤痘病毒感染。传染性软疣病毒（MCV）表达几种参与其发病机制和逃避宿主免疫系统的基因产物。MCV可通过直接身体接触以及污染物传播至身体的其他部位和其他个体。虽然临床上诊断通常很简单，但传染性软疣的治疗存在争议。有几种治疗方法可用于破坏单个皮损，但没有足够的证据表明治疗干预比自然、自发消退更有效。复杂病例，如免疫功能低下患者和黏膜皮肤部位发生的感染，需要采用替代的管理方法。传染性软疣仍然是全球儿童和家长的负担。
