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[主动脉瓣和二尖瓣置换术后溶血性贫血所揭示的离散型主动脉瓣下狭窄]

[Discrete type subaortic stenosis disclosed by hemolytic anemia after aortic and mitral valve replacement].

作者信息

Kawahara Yu, Inage Yuichi, Masaki Naoki, Kobayashi Yuriko, Jinbu Ryota, Toyama Shuji, Fukasawa Manabu

机构信息

Department of Cardiovascular Surgery, Yamagata Prefectural Central Hospital, Yamagata, Japan.

出版信息

Kyobu Geka. 2014 Mar;67(3):215-9.

Abstract

We report a case of discrete type subaortic stenosis disclosed by hemolytic anemia 7 years after aortic and mitral prosthetic valve replacement. A 53-year-old female complained of general fatigue, dyspnea, macrohematuria and hemolysis. She had undergone aortic valve replacement for non-coronary cusp perforation 15 years before, and mitral valve replacement and tricuspid annuloplasty 7 years before. Echocardiography showed mitral prosthetic valve regurgitation (III/IV degree) and symptomatic hemolysis might be caused by accelerated blood flow through the prosthetic valve. A mild aortic stenosis (peak flow verocity:3.73 m/s) was also pointed out. The redo double valve replacement was performed. Intraoperative findings showed discrete type subaortic stenosis due to extensive pannus formation, but that the previously implanted prosthetic valves were intact. The blood flow biased by the interference of the subaortic stenosis might have obstructed closure of the mitral prosthetic valve and caused mitral regurgitation. Postoperatively, hemolysis and mitral regurgitation were diminished, and aortic stenosis was improved.

摘要

我们报告一例在主动脉瓣和二尖瓣人工瓣膜置换术后7年因溶血性贫血而发现的离散型主动脉瓣下狭窄病例。一名53岁女性主诉全身乏力、呼吸困难、肉眼血尿和溶血。她15年前因非冠状动脉瓣叶穿孔接受了主动脉瓣置换术,7年前接受了二尖瓣置换术和三尖瓣环成形术。超声心动图显示二尖瓣人工瓣膜反流(III/IV级),症状性溶血可能是由于通过人工瓣膜的血流加速所致。还指出存在轻度主动脉瓣狭窄(峰值流速:3.73米/秒)。遂进行了再次双瓣膜置换术。术中发现由于广泛的血管翳形成导致离散型主动脉瓣下狭窄,但先前植入的人工瓣膜完好无损。主动脉瓣下狭窄的干扰使血流偏向,可能阻碍了二尖瓣人工瓣膜的关闭并导致二尖瓣反流。术后,溶血和二尖瓣反流减轻,主动脉瓣狭窄得到改善。

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