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一名免疫功能正常、出现单侧颈部肿块的患者中偶然分枝杆菌的误诊。

Misidentification of Mycobacterium fortuitum in an immunocompetent patient presenting with a unilateral neck mass.

作者信息

Kanzara Todd, Hall Andy, Namnyak Simon, Owa Tony

机构信息

Department of Surgery, East and North Hertfordshire NHS Trust, Stevenage, Hertfordshire, UK.

出版信息

BMJ Case Rep. 2014 Apr 17;2014:bcr2014203857. doi: 10.1136/bcr-2014-203857.

Abstract

A 31-year-old African man with a blameless medical history presented with an enlarging neck swelling of 6 months duration. He was systemically well with normal heamatobiochemistry. MRI of the neck demonstrated abnormal signalling in the subcutaneous fat overlying the posterior spinal muscles in the midline and the left sternocleidomastoid muscle. Scanty growth of Rhodococcus equi was reported from a turbid fine needle aspirate of the neck on two separate occasions. The swelling progressed despite numerous antibiotic combinations which necessitated surgical debridement. Analysis of debrided tissue using 16S rDNA surprisingly identified Mycobacterium fortuitum, not R equi, thereby resolving our diagnostic conundrum.

摘要

一名31岁无不良病史的非洲男子,颈部肿物逐渐增大,病程6个月。他全身状况良好,血液生化指标正常。颈部磁共振成像(MRI)显示,中线和左侧胸锁乳突肌后方脊柱旁肌肉上方皮下脂肪有异常信号。在两次颈部细针穿刺抽吸混浊样本中均报告有少量马红球菌生长。尽管使用了多种抗生素联合治疗,肿物仍继续进展,因此需要进行手术清创。令人惊讶的是,使用16S核糖体DNA(rDNA)对清创组织进行分析后发现是偶然分枝杆菌,而非马红球菌,从而解决了我们的诊断难题。

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