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重症间日疟原虫疟疾合并急性呼吸窘迫综合征:希腊一例与局灶性本地传播相关的病例

Severe Plasmodium vivax malaria complicated with acute respiratory distress syndrome: a case associated with focal autochthonous transmission in Greece.

作者信息

Gougoutsi Alexandra, Karageorgopoulos Drosos E, Dimitriadou Areti, Melas Nikolaos, Kranidiotis Georgios, Voutsinas Dionysios, Melidonis Andreas

机构信息

1 Department of Internal Medicine, Tzaneio General Hospital , Piraeus, Greece .

出版信息

Vector Borne Zoonotic Dis. 2014 May;14(5):378-81. doi: 10.1089/vbz.2012.1192. Epub 2014 Apr 18.

DOI:10.1089/vbz.2012.1192
PMID:24745658
Abstract

In 2011, autochthonous Plasmodium vivax malaria emerged in a focal geographical area in Greece after importation by immigrants from the Indian subcontinent. We report the case of complicated P. vivax malaria in a previously healthy 42-year-old Greek female. The patient presented acute respiratory distress syndrome (ARDS), worsening jaundice, and thrombocytopenia after the administration of antimalarial treatment and despite a decreasing burden of parasitemia. She recovered fully after admission in the intensive care unit and support with mechanical ventilation. We discuss the risks potentially associated with the reappearance of P. vivax malaria in a previously malaria-free area.

摘要

2011年,在来自印度次大陆的移民输入疟原虫后,希腊一个局部地理区域出现了本土间日疟原虫疟疾。我们报告了一例先前健康的42岁希腊女性患复杂间日疟原虫疟疾的病例。该患者在接受抗疟治疗后出现急性呼吸窘迫综合征(ARDS)、黄疸加重和血小板减少,尽管疟原虫血症负担有所减轻。她在重症监护病房住院并接受机械通气支持后完全康复。我们讨论了在一个先前无疟疾的地区间日疟原虫疟疾再次出现可能相关的风险。

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