Program of Excellence in Mast Cell and Eosinophil Disorders, Division of Allergic Disease, Department of Internal Medicine, W-15 Mayo Building, 200 First Street Southwest, Rochester, MN 55905, USA.
Program of Excellence in Mast Cell and Eosinophil Disorders, Division of Allergic Disease, Department of Internal Medicine, W-15 Mayo Building, 200 First Street Southwest, Rochester, MN 55905, USA.
Immunol Allergy Clin North Am. 2014 May;34(2):423-32. doi: 10.1016/j.iac.2014.01.004. Epub 2014 Mar 13.
Mast cell sarcoma is a disorder that results in abnormal mast cells as identified by morphology, special stains, and in some publications, c-kit mutation analysis. It affects animal species such as canines more commonly than humans. In humans it is a very rare condition, with variable clinical presentation. There is no standard therapy for the disorder. It can affect any age group. It is occasionally associated with systemic mastocytosis and/or urticaria pigmentosa. The prognosis of mast cell sarcoma in published literature is very poor in humans.
肥大细胞瘤肉瘤是一种疾病，其特征为形态学、特殊染色和在一些出版物中 c-kit 突变分析显示异常肥大细胞。它比人类更常见于犬科等动物物种。在人类中，它是一种非常罕见的疾病，临床表现多样。该疾病没有标准的治疗方法。它可以影响任何年龄段。它偶尔与系统性肥大细胞增多症和/或色素性荨麻疹有关。在已发表的文献中，人类肥大细胞瘤肉瘤的预后非常差。
