Broniarz-Press L, Ochowiak M, Matuszak M, Włodarczak S
Poznan University of Technology, Faculty of Chemical Technology, Department of Chemical Engineering and Equipment, Poznan, Poland.
Poznan University of Technology, Faculty of Chemical Technology, Department of Chemical Engineering and Equipment, Poznan, Poland.
Int J Pharm. 2014 Jul 1;468(1-2):199-206. doi: 10.1016/j.ijpharm.2014.04.032. Epub 2014 Apr 16.
The paper contains the results of experimental studies of water, aqueous solutions of glycerol and aqueous solutions of glycerol-polyethylene oxide (PEO) atomization process in a medical inhaler obtained by the use of the digital microphotography method. The effect of the shear and extensional viscosity on the drop size, drop size histogram and mean drop diameter has been analyzed. The obtained results have shown that the drop size increases with the increase in shear and extensional viscosity of liquid atomized. Extensional viscosity has a greater impact on the spraying process. It has been shown that the change in liquid viscosity leads to significant changes in drop size distribution. The correlation for Sauter mean diameter as function of the shear and extensional viscosity was proposed.
