Classen T, von Knoch M, Wernsmann M, Landgraeber S, Löer F, Jäger M
Orthopaedic Department, University of Duisburg - Essen Medical School, Hufelandstrasse 55, 45147 Essen, Germany.
Orthopaedic Department, Hospital of Bremerhaven, Bremerhaven, Germany.
Orthop Traumatol Surg Res. 2014 Jun;100(4):409-12. doi: 10.1016/j.otsr.2014.01.010. Epub 2014 Apr 18.
Deep periprosthetic infection is one of the most serious complications after total knee replacement. The two-stage procedure with implantation of a temporary cement spacer and later re-implantation of a revision total knee prosthesis is an accepted procedural standard. The use of articulating spacers has been proposed to enhance ease of revision and functional results.
Twenty-three patients treated with an articulating spacer were retrospectively studied. All patients had undergone a two-stage surgery. The infected prosthesis was explanted and the femoral component was sterilized and re-implanted. On the tibial side a block of gentamicin-loaded bone cement was produced intraoperatively using specially manufactured templates. Eighteen total knee arthroplasty revisions and 5 arthrodesis were finally performed.
A total of three (13%) re-infections occurred 5-20 months after revision total knee arthroplasty in a mean follow-up period of 47 months. Prior to re-implantation, flexion with the articulating spacer ranged between 15 and 100° (mean 68±28°). The average postoperative flexion after re-implantation of total knee replacement was 105±11°.
The articulating spacer used in this study appears to be as effective as the standard procedures in terms of re-infection risk rate and postoperative range of motion recovery.
Level IV.
深部假体周围感染是全膝关节置换术后最严重的并发症之一。采用临时骨水泥间隔物植入并随后再次植入翻修全膝关节假体的两阶段手术是公认的手术标准。有人提出使用活动式间隔物以提高翻修的便利性和功能效果。
对23例采用活动式间隔物治疗的患者进行回顾性研究。所有患者均接受了两阶段手术。取出感染的假体,对股骨部件进行消毒并重新植入。在胫骨侧,术中使用特制模板制作一块载有庆大霉素的骨水泥块。最终进行了18例全膝关节置换翻修手术和5例关节融合术。
在平均47个月的随访期内,翻修全膝关节置换术后5至20个月共发生3例(13%)再次感染。重新植入前,使用活动式间隔物时的屈曲角度在15至100°之间(平均68±28°)。全膝关节置换重新植入后的平均术后屈曲角度为105±11°。
本研究中使用的活动式间隔物在再次感染风险率和术后活动度恢复方面似乎与标准手术同样有效。
四级