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引起肾综合征出血热的病毒的病毒粒子蛋白;单克隆抗体分析

Virion proteins of viruses causing hemorrhagic fever with renal syndrome; monoclonal antibody analysis.

作者信息

Yang D L, Hao L J, Ni D S, Zhou N

出版信息

J Tongji Med Univ. 1989;9(1):13-7. doi: 10.1007/BF02933737.

DOI:10.1007/BF02933737
PMID:2474668
Abstract

SDS-polyacrylamide gel electrophoresis and Western blotting analysis by using 9 clones of monoclonal antibodies specific for hemorrhagic fever with renal syndrome (HFRS) viruses were carried out on the virion proteins of 17 strains of HFRS viruses isolated from different areas in Asia and different hosts such as Apodemus agrarius, Rattus norvegicus, domestic cat and HFRS patients. Polypeptide with apparent molecular weight about 50 kitodalton (Kd) could be detected in all 17 strains of HFRS viruses. On this polypeptide there are two different antigenic determinants and one of them might be genus specific.

摘要

利用9株对肾综合征出血热(HFRS)病毒特异的单克隆抗体,对从亚洲不同地区以及黑线姬鼠、褐家鼠、家猫和HFRS患者等不同宿主分离出的17株HFRS病毒的病毒粒子蛋白进行了SDS-聚丙烯酰胺凝胶电泳和蛋白质印迹分析。在所有17株HFRS病毒中均可检测到表观分子量约为50千道尔顿(Kd)的多肽。在该多肽上存在两种不同的抗原决定簇,其中之一可能是属特异性的。

相似文献

1
Virion proteins of viruses causing hemorrhagic fever with renal syndrome; monoclonal antibody analysis.引起肾综合征出血热的病毒的病毒粒子蛋白;单克隆抗体分析
J Tongji Med Univ. 1989;9(1):13-7. doi: 10.1007/BF02933737.
2
Characterization of glycoproteins of viruses causing hemorrhagic fever with renal syndrome (HFRS) using monoclonal antibodies.利用单克隆抗体对肾综合征出血热(HFRS)病毒糖蛋白进行特性分析。
Virology. 1986 Jun;151(2):379-84. doi: 10.1016/0042-6822(86)90058-9.
3
The antigenic analysis of haemorrhagic fever with renal syndrome viruses in China by monoclonal antibodies.应用单克隆抗体对我国肾综合征出血热病毒进行抗原分析
J Hyg (Lond). 1986 Oct;97(2):369-75. doi: 10.1017/s0022172400065451.
4
Determination by immune adherence HA of the antigenic relationship between Rattus- and Apodemus-borne viruses causing hemorrhagic fever with renal syndrome.用免疫粘附血凝试验确定家鼠型和姬鼠型肾综合征出血热病毒之间的抗原关系
J Infect Dis. 1984 Mar;149(3):472. doi: 10.1093/infdis/149.3.472.
5
Four serotypes of haemorrhagic fever with renal syndrome viruses identified by polyclonal and monoclonal antibodies.
J Gen Virol. 1987 Apr;68 ( Pt 4):979-87. doi: 10.1099/0022-1317-68-4-979.
6
[Antigenic analysis of hemorrhagic fever with renal syndrome viruses (HFRS) using monoclonal antibodies].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1987 Dec;9(6):428-32.
7
Serological characterization of a hantavirus from Hubei, China.中国湖北一种汉坦病毒的血清学特征
Acta Virol. 2004;48(1):5-8.
8
[Use of monoclonal antibodies for differentiating strains of the virus causing the hemorrhagic fever with renal syndrome].
Vopr Virusol. 1987 Sep-Oct;32(5):604-7.
9
Antigenic differences between two viruses, isolated in Japan and Korea, that cause hemorrhagic fever with renal syndrome.在日本和韩国分离出的两种导致肾综合征出血热的病毒之间的抗原差异。
J Virol. 1984 Oct;52(1):231-7. doi: 10.1128/JVI.52.1.231-237.1984.
10
A serotypic study of hemorrhagic fever with renal syndrome in rural China.中国农村肾综合征出血热的血清型研究。
Am J Trop Med Hyg. 1995 Mar;52(3):247-51. doi: 10.4269/ajtmh.1995.52.247.

本文引用的文献

1
Hemagglutination-inhibiting antibody in hemorrhagic fever with renal syndrome.肾综合征出血热中的血凝抑制抗体。
J Infect Dis. 1984 Dec;150(6):895-8. doi: 10.1093/infdis/150.6.895.
2
Antigenic difference between viral strains causing classical and mild types of epidemic hemorrhagic fever with renal syndrome in China.在中国引起肾综合征出血热典型和轻型的病毒株之间的抗原差异。
J Infect Dis. 1984 Dec;150(6):889-94. doi: 10.1093/infdis/150.6.889.
3
Molecular weight determination of protein-dodecyl sulfate complexes by gel electrophoresis in a discontinuous buffer system.
在不连续缓冲系统中通过凝胶电泳测定蛋白质 - 十二烷基硫酸盐复合物的分子量
J Biol Chem. 1971 Oct 25;246(20):6328-34.
4
Hantaan virus M RNA: coding strategy, nucleotide sequence, and gene order.汉坦病毒M RNA:编码策略、核苷酸序列及基因顺序。
Virology. 1987 Mar;157(1):31-9. doi: 10.1016/0042-6822(87)90310-2.
5
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.蛋白质从聚丙烯酰胺凝胶到硝酸纤维素膜的电泳转移:方法及一些应用
Proc Natl Acad Sci U S A. 1979 Sep;76(9):4350-4. doi: 10.1073/pnas.76.9.4350.