Center for Advanced Orthopedics at Larkin, Miami, Florida.
Arthritis Surgery Research Foundation, Miami, Florida.
J Arthroplasty. 2014 Aug;29(8):1681-6. doi: 10.1016/j.arth.2014.03.010. Epub 2014 Mar 15.
Bone mineral density (BMD), as measured by DEXA, can vary depending on bone rotation and fat content of soft tissues. We performed DEXA measurements, under controlled positioning, on 24 autopsy-retrieved femora from patients who had fully functional and asymptomatic successful TKA to determine periprosthetic BMD changes and compared results to 24 normal cadaveric femora. In TKA specimens, BMD was affected by gender, preoperative diagnosis, and zone under analysis. The lowest mean BMD was in the anterior femoral condylar zone. Males had higher mean BMD at all zones while patients with preoperative diagnosis of osteoarthritis had higher BMD in the posterior condylar zone. The mean BMD in the anterior femoral condylar zone in TKA specimens was significantly lower than in normal specimens without arthroplasties, most likely due to stress shielding.
骨密度（BMD），通过 DEXA 测量，可以根据骨骼旋转和软组织的脂肪含量而有所不同。我们对 24 例功能齐全且无症状的成功 TKA 患者的尸体股骨进行了 DEXA 测量，以确定假体周围 BMD 的变化，并将结果与 24 例正常尸体股骨进行了比较。在 TKA 标本中，BMD 受性别、术前诊断和分析区域的影响。前股骨髁区的平均 BMD 最低。男性在所有区域的平均 BMD 均较高，而术前诊断为骨关节炎的患者在后髁区的 BMD 较高。TKA 标本中前股骨髁区的平均 BMD 明显低于未进行关节置换的正常标本，这很可能是由于应力屏蔽所致。
