圈养日本猕猴（Macaca fuscata）中日本脑炎病毒感染的血清流行率。

Seroprevalence of Japanese encephalitis virus infection in captive Japanese macaques (Macaca fuscata).

作者信息

Shimoda Hiroshi, Saito Akatsuki, Noguchi Keita, Terada Yutaka, Kuwata Ryusei, Akari Hirofumi, Takasaki Tomohiko, Maeda Ken

机构信息

Laboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, Yamaguchi, 753-8515, Japan.

出版信息

Primates. 2014 Jul;55(3):441-5. doi: 10.1007/s10329-014-0421-7. Epub 2014 Apr 19.

DOI:10.1007/s10329-014-0421-7

PMID:24748049

Abstract

Japanese encephalitis virus (JEV), which is transmitted by mosquitoes, infects many animal species and causes serious acute encephalitis in humans and horses. In this study, a serosurvey of JEV in Japanese macaques (Macaca fuscata) reared in Aichi Prefecture was conducted using purified JEV as an antigen for ELISA. The results revealed that 146 of 332 monkeys (44 %) were seropositive for JEV. In addition, 35 of 131 monkeys (27 %) born in the facility were seropositive, and the annual infection rate in the facility was estimated as 13 %. Our results provide evidence of the frequent exposure of many Japanese macaques to JEV, suggesting that there is a risk of JEV transmission to humans by mosquitoes.

摘要

日本脑炎病毒（JEV）通过蚊子传播，可感染多种动物，并在人类和马匹中引发严重的急性脑炎。在本研究中，以纯化的JEV作为酶联免疫吸附测定（ELISA）的抗原，对饲养于爱知县的日本猕猴（Macaca fuscata）进行了JEV血清学调查。结果显示，332只猴子中有146只（44%）JEV血清学呈阳性。此外，在该饲养场所出生的131只猴子中有35只（27%）血清学呈阳性，该饲养场所的年感染率估计为13%。我们的结果证明许多日本猕猴经常接触JEV，这表明存在蚊子将JEV传播给人类的风险。