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特发性炎性肌病患者发生静脉血栓栓塞的风险:一项系统评价和荟萃分析

Risk of venous thromboembolism in patients with idiopathic inflammatory myositis: a systematic review and meta-analysis.

作者信息

Ungprasert Patompong, Sanguankeo Anawin

机构信息

Department of Internal Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand,

出版信息

Rheumatol Int. 2014 Oct;34(10):1455-8. doi: 10.1007/s00296-014-3023-1. Epub 2014 Apr 20.

Abstract

We performed this meta-analysis to assess venous thromboembolism risk in patients with idiopathic inflammatory myositis (IIM). A comprehensive search was performed in MEDLINE, EMBASE and the Cochrane database. Three observational studies met our inclusion criteria and were included in the data analysis. The pooled risk ratio of venous thromboembolism in patients with IIM compared with non-IIM participants was 2.85 (95 % CI 2.12-3.84). Our result indicates a significant increased risk of venous thromboembolism among patients with IIM.

摘要

我们进行了这项荟萃分析,以评估特发性炎症性肌病(IIM)患者发生静脉血栓栓塞的风险。我们在MEDLINE、EMBASE和Cochrane数据库中进行了全面检索。三项观察性研究符合我们的纳入标准,并被纳入数据分析。与非IIM参与者相比,IIM患者发生静脉血栓栓塞的合并风险比为2.85(95%CI 2.12 - 3.84)。我们的结果表明,IIM患者发生静脉血栓栓塞的风险显著增加。

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