Gur'ianov V A, Nosenko M M, Gadzhibekov N Ch, Ialich A Iu, Aliautdin R N, Tolmachev G N
Anesteziol Reanimatol. 2013 Nov-Dec(6):21-4.
Comparative study of postoperative analgesia and sedation with trimeperidine and dexmedetomidine and their effects on haemodynamics and vegetative nervous system was performed. Assessment of analgesia and sedation during vagotonia (first part of the study) and hypokinetic type of haemodynamics (second part of the study) was carried out with visual analogue scale (VAS) and Richmond scale. Results of the study showed that dexmedetomidine is more effective and safer than trimeperidine for analgesia and sedation in patients with spontaneous breathing after abdominal surgery. Dexmedetomidine use allows keeping optimal type of haemodynamics and vegetative nervous system parameters on first day of postoperative period.
进行了哌替啶和右美托咪定术后镇痛与镇静及其对血流动力学和自主神经系统影响的比较研究。在迷走神经紧张（研究的第一部分）和低动力型血流动力学（研究的第二部分）期间，采用视觉模拟量表（VAS）和里士满量表对镇痛和镇静进行评估。研究结果表明，在腹部手术后自主呼吸患者的镇痛和镇静方面，右美托咪定比哌替啶更有效、更安全。使用右美托咪定可在术后第一天维持最佳的血流动力学类型和自主神经系统参数。
