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探索慢性肾病队列中健康状况、疾病认知、应对策略与心理发病率之间的关系。

Exploring the relationships between health status, illness perceptions, coping strategies and psychological morbidity in a chronic kidney disease cohort.

作者信息

Knowles Simon, Swan Lauren, Salzberg Michael, Castle David, Langham Robyn

机构信息

Department of Psychology (SK, LS), Swinburne University of Technology, Melbourne, Australia; and Departments of Psychiatry (SK, MS, DC), Department of Nephrology (RL) St. Vincent's Hospital, Melbourne, Australia.

出版信息

Am J Med Sci. 2014 Oct;348(4):271-6. doi: 10.1097/MAJ.0000000000000242.

Abstract

BACKGROUND

Using the common sense model of illness adjustment, this study aimed to explore the impact of chronic kidney disease (CKD) on individual illness perceptions, coping styles and psychological well-being.

METHODS

Eighty individuals (50 men and 30 women) with an average age of 62.66 years (standard deviation, 11.98) were included in the study. All participants were under the care of the Renal Unit of a metropolitan tertiary referral hospital. Twenty-nine patients (36%) had CKD stage 3b-4, and 51 (64%) had CKD stage 5 (or end stage kidney disease [ESKD]). Disease severity was evaluated using the health perceptions questionnaire, coping styles assessed with the Carver brief COPE scale, illness perceptions explored with the brief illness perceptions questionnaire and anxiety and depression measured using the hospital anxiety and depression scale.

RESULTS

The hospital anxiety and depression scale assessment revealed 13 patients (16.3%) with moderate or severe anxiety and 6 (7.5%) with moderate depression. Consistent with the common sense model, disease activity had a significant direct influence on illness perceptions, while, in turn, illness perceptions had a significant direct influence on depression and anxiety. Adaptive and maladaptive coping were found to mediate the relationship between illness perceptions, and anxiety and depression.

CONCLUSIONS

The results provide evidence that it is the perception of an illness rather than the actual symptoms themselves that best account for adaption to CKD. These findings suggest that intervention strategies aimed at increasing psychological well-being need to focus on changing illness perceptions rather than improving symptoms of CKD or coping mechanisms.

摘要

背景

本研究采用疾病适应常识模型,旨在探讨慢性肾脏病(CKD)对个体疾病认知、应对方式和心理健康的影响。

方法

本研究纳入了80名个体(50名男性和30名女性),平均年龄为62.66岁(标准差为11.98)。所有参与者均在一家大都市三级转诊医院的肾脏科接受治疗。29名患者(36%)处于CKD 3b - 4期,51名患者(64%)处于CKD 5期(或终末期肾病[ESKD])。使用健康认知问卷评估疾病严重程度,使用卡弗简易应对方式量表评估应对方式,使用简易疾病认知问卷探索疾病认知,并使用医院焦虑抑郁量表测量焦虑和抑郁。

结果

医院焦虑抑郁量表评估显示,13名患者(16.3%)有中度或重度焦虑,6名患者(7.5%)有中度抑郁。与常识模型一致,疾病活动对疾病认知有显著的直接影响,而疾病认知又对抑郁和焦虑有显著的直接影响。发现适应性和适应不良应对方式在疾病认知与焦虑和抑郁之间的关系中起中介作用。

结论

结果表明,最能解释对CKD适应情况的是疾病认知而非实际症状本身。这些发现表明,旨在提高心理健康水平的干预策略需要侧重于改变疾病认知,而不是改善CKD症状或应对机制。

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