Clark Natalie A, Mumford Sunni L, Segars James H
aDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan bEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development cProgram in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
Curr Opin Obstet Gynecol. 2014 Jun;26(3):151-61. doi: 10.1097/GCO.0000000000000070.
Magnetic-resonance-guided focused ultrasound surgery (MRgFUS) is a minimally invasive technique for the treatment of uterine fibroids. The purpose of this review is to highlight the impact of MRgFUS on fertility and reproductive outcomes.
The role of MRgFUS in the treatment of fibroids has been evolving since its introduction in 2004. Several new devices and techniques including location-specific treatment, volumetric therapy, and vessel-targeted therapy have been introduced over the last few years. Several case series report uncomplicated pregnancy following MRgFUS; however, results of the ongoing studies will further elucidate the utility of MRgFUS in patients planning future fertility. A systematic review of the literature was completed and studies that reported quality of life at baseline and after 6 months were included in a meta-analysis.
MRgFUS represents a minimally invasive treatment for uterine fibroids that is able to improve the quality of life and fibroid size with durability. It is possible that MRgFUS could be the treatment of choice for patients desiring future fertility; however, further investigation is needed.
磁共振引导聚焦超声手术（MRgFUS）是一种治疗子宫肌瘤的微创技术。本综述的目的是强调MRgFUS对生育能力和生殖结局的影响。
自2004年引入以来，MRgFUS在子宫肌瘤治疗中的作用一直在不断发展。在过去几年中，已经推出了几种新设备和技术，包括定位特异性治疗、容积治疗和血管靶向治疗。几个病例系列报告了MRgFUS后无并发症的妊娠情况；然而，正在进行的研究结果将进一步阐明MRgFUS在计划未来生育的患者中的效用。完成了对文献的系统综述，并将报告基线和6个月后生活质量的研究纳入荟萃分析。
MRgFUS是一种能够持久改善生活质量和缩小肌瘤大小的子宫肌瘤微创治疗方法。对于希望未来生育的患者，MRgFUS有可能成为首选治疗方法；然而，还需要进一步研究。
