Fedorko L, Hoskin R W, Duffin J
Mt. Sinai Hospital Research Institute, Toronto, Ontario, Canada.
Exp Neurol. 1989 Sep;105(3):306-10. doi: 10.1016/0014-4886(89)90134-9.
The connection between the inspiratory neurons of the nucleus retroambigualis and the phrenic motoneurons was examined using the techniques of antidromic mapping to discover collaterals and spike-triggered averaging to detect postsynaptic potentials. Axon collaterals within the region of the C5 phrenic nucleus were found for 17 of 26 (65%) inspiratory neurons and 6 of these 17 (35%) were shown to generate excitatory postsynaptic potentials in at least one phrenic motoneuron. It was concluded that these results demonstrate a strong connection for those inspiratory neurons of the nucleus retroambigualis with a collateral within the phrenic nucleus.
