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微腔光流体学:染料激光器和生物传感器。

Optofluidic microcavities: Dye-lasers and biosensors.

机构信息

Department of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, China ; Ecole Normale Supérieure, CNRS-ENS-UPMC, 24 rue Lhomond, 75231 Paris, France ; Centre for Microfluidics and Nanotechnology, Peking University, 100871 Beijing, China.

Department of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, China ; Ecole Normale Supérieure, CNRS-ENS-UPMC, 24 rue Lhomond, 75231 Paris, France.

出版信息

Biomicrofluidics. 2010 Dec 30;4(4):043002. doi: 10.1063/1.3499949. eCollection 2010 Dec.

Abstract

Optofluidic microcavities are integrated elements of microfluidics that can be explored for a large variety of applications. In this review, we first introduce the physics basis of optical microcavities and microflow control. Then, we describe four types of optofluidic dye lasers developed so far based on both simple and advanced device fabrication technologies. To illustrate the application potential of such devices, we present two types of laser intracavity measurements for chemical solution and single cell analyses. In addition, the possibility of single molecule detection is discussed. All these recent achievements demonstrated the great importance of the topics in biology and several other disciplines.

摘要

光流微腔是微流控的集成元件,可以探索各种应用。在这篇综述中,我们首先介绍了光学微腔和微流控制的物理基础。然后,我们描述了迄今为止基于简单和先进的器件制造技术开发的四种光流体染料激光器。为了说明这些器件的应用潜力,我们提出了两种用于化学溶液和单细胞分析的激光腔内测量方法。此外,还讨论了单分子检测的可能性。所有这些最新的成果都证明了这些在生物学和其他几个学科中的主题的重要性。

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