Penzlin H, Wieduwilt I, Hertel W
Department of Animal Physiology, Friedrich-Schiller-University of Jena, German Democratic Republic.
Gen Comp Endocrinol. 1989 Jul;75(1):88-95. doi: 10.1016/0016-6480(89)90012-9.
It is shown that the isolated oviduct as well as the proctodeum of the cockroach Periplaneta americana are sensitive to substance P application. In contrast, the hyperneural muscle and the dilator muscle of the antennal heart were insensitive to this neuropeptide. The entire substance P amino acid sequence is necessary for the effects. This provides evidence for a pharmacological effect of substance P in insects.
研究表明，美洲大蠊分离出的输卵管以及后肠对施用的P物质敏感。相比之下，触角心脏的超神经肌肉和扩张肌对这种神经肽不敏感。P物质的完整氨基酸序列对这些效应是必需的。这为P物质在昆虫中的药理作用提供了证据。
