Kumar Anup, Vasudeva Pawan, Kumar Niraj, Nanda Biswajit, Jha Sanjeev Kumar, Kumar Rohit, Singh Harbinder
Department of Urology and Renal Transplant, Vardhman Mahavir Medical College and Safdarjung Hospital , New Delhi, India .
J Endourol. 2014 Sep;28(9):1115-20. doi: 10.1089/end.2014.0170. Epub 2014 Jul 2.
Photoselective vaporization of prostate (PVP) by 120W HPS laser emerged as an efficient, bloodless, and durable first line alternative to transurethral resection of prostate for treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic enlargement (BPE). In this study, we assessed effects of PVP by HPS laser on erectile function.
Between January 2012 and February 2014, 143 consecutive patients presenting with LUTS secondary to BPE, who underwent PVP by 120W HPS laser, were prospectively enrolled in the study. Patient's (Group A: International Index of Erectile Function-5 (IIEF-5) ≥19; Group B: IIEF <19) preoperative, perioperative and follow-up data were recorded. IIEF-5 was used to assess preoperative and postoperative erectile function at 1, 3, 6, and 12 months. Recorded data was analyzed statistically.
Preoperative and perioperative data of the two groups were comparable. Significant improvement in IPSS, Qmax, QoL, and post void residual urine at 1, 3, 6 and 12 months were observed in both groups with no significant difference between them. Although IIEF-5 scores declined in both groups postoperatively (Group A: 21.06±1.21 to 19.84±1.55, P=0.43; Group B: 14.67±2.05 to 12.79±1.42, P=0.53), it was not statistically significant in either group. No significant difference was noted in IIEF-5 score between patients with or without indwelling catheter in either of the two groups.
In patients undergoing PVP by 120W HPS laser for LUTS secondary to BPE, no significant effect was observed in sexual function at 1 year follow-up.
120W高功率半导体（HPS）激光前列腺选择性汽化术（PVP）已成为治疗良性前列腺增生（BPE）继发下尿路症状（LUTS）的一种有效、无血且持久的一线替代经尿道前列腺切除术的方法。在本研究中，我们评估了HPS激光PVP对勃起功能的影响。
2012年1月至2014年2月，连续143例因BPE继发LUTS且接受120W HPS激光PVP的患者被前瞻性纳入本研究。记录患者（A组：国际勃起功能指数-5（IIEF-5）≥19；B组：IIEF＜19）的术前、围手术期和随访数据。使用IIEF-5评估术前以及术后1、3、6和12个月的勃起功能。对记录的数据进行统计学分析。
两组的术前和围手术期数据具有可比性。两组在术后1、3、6和12个月时国际前列腺症状评分（IPSS）、最大尿流率（Qmax）、生活质量（QoL）和残余尿量均有显著改善，且两组间无显著差异。虽然两组术后IIEF-5评分均下降（A组：21.06±1.21降至19.84±1.55，P = 0.43；B组：14.67±2.05降至12.79±1.42，P = 0.53），但两组均无统计学意义。两组中留置或未留置导尿管的患者之间IIEF-5评分无显著差异。
对于因BPE继发LUTS而接受120W HPS激光PVP的患者，在1年随访中未观察到性功能有显著影响。
