Ouyang Yun, Liu Cuilong, Guan Weimin, Zhao Yubo, Xu Yansheng, Wu Yiguang
Department of Urology, Navy General Hospital of the Chinese People's Liberation Army , Haidian District, Beijing, China .
Photomed Laser Surg. 2014 Aug;32(8):463-7. doi: 10.1089/pho.2014.3727.
Our aim was to evaluate the impact of 160 W Greenlight laser vaporization of the prostate on erectile function by the International Index of Erectile Function (IIEF-5) in 1-year follow-up in patients with lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH).
Although high-power Greenlight laser has greatly improved the efficiency of vaporization of the prostate, the impact of it on erectile function remains uncertain.
A total of 80 BPH patients with normal erectile function or mild erectile dysfunction (IIEF-5 ≥12) were included in this study. They were randomly assigned to two equal groups: 80 or 160 W. Both groups were compared regarding all relevant preoperative, operative, and postoperative parameters. Urinary function in terms of International Prostate Symptom Score (IPSS), quality of life (QOL) score, maximum flow rate (Qmax), and residual urinary volume (RUV) were evaluated at 1, 3, 6, and 12 months postoperatively. Erectile function was evaluated by IIEF-5 at 3, 6, and 12 months postoperatively.
Baseline characteristics of the two groups were comparable. Mean operative time was significantly shorter for the 160 W group. Urinary function in terms of IPSS, QOL, Qmax, and RUV were all significantly improved over baseline in both groups. There were no significant differences in these urinary functional parameters between the two groups at any point of follow-up. IIEF-5 scores of both groups significantly decreased at 3 months postoperatively compared with baseline, but at 6 and 12 months postoperatively, IIEF-5 score of either group increased to baseline, and was not different from baseline. At any point of follow-up, IIEF-5 scores of the two groups were comparable.
Greenlight laser (160 W) vaporization of the prostate will not increase the risk of impairing erectile function.
我们的目的是通过国际勃起功能指数（IIEF-5）评估160W绿激光前列腺汽化术对良性前列腺增生（BPH）所致下尿路症状（LUTS）患者勃起功能的影响，并进行为期1年的随访。
尽管高功率绿激光极大地提高了前列腺汽化效率，但它对勃起功能的影响仍不确定。
本研究共纳入80例勃起功能正常或轻度勃起功能障碍（IIEF-5≥12）的BPH患者。他们被随机分为两组，每组40例：80W组和160W组。比较两组所有相关的术前、术中及术后参数。术后1、3、6和12个月评估国际前列腺症状评分（IPSS）、生活质量（QOL）评分、最大尿流率（Qmax）和残余尿量（RUV）方面的排尿功能。术后3、6和12个月通过IIEF-5评估勃起功能。
两组的基线特征具有可比性。160W组的平均手术时间明显更短。两组在IPSS、QOL、Qmax和RUV方面的排尿功能均较基线有显著改善。在随访的任何时间点，两组之间这些排尿功能参数均无显著差异。两组的IIEF-5评分在术后3个月时较基线均显著降低，但在术后6个月和12个月时，两组的IIEF-5评分均升至基线水平，且与基线无差异。在随访的任何时间点，两组的IIEF-5评分均具有可比性。
160W绿激光前列腺汽化术不会增加损害勃起功能的风险。
