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肾交感神经去神经支配后异常的血管反应是否预示着永久性损伤?能量输送后晚期肾动脉狭窄的一个不寻常病例。

Is an abnormal vascular response after renal sympathetic denervation predictive of permanent damage? An unusual case of late renal artery stenosis after energy delivery.

机构信息

1 Department of Cardiovascular Disease, Ospedale "Antonio Cardarelli," Campobasso, Italy.

出版信息

J Endovasc Ther. 2014 Apr;21(2):191-6. doi: 10.1583/13-4574MR.1.

DOI:10.1583/13-4574MR.1
PMID:24754277
Abstract

PURPOSE

To describe the effect of renal sympathetic denervation (RDN) on renal arteries immediately after the procedure and at follow-up.

CASE REPORT

A 52-year-old woman with severe resistant hypertension underwent RDN. A transient spasm occurred in the left renal artery immediately after radiofrequency energy delivery, with subsequent complete resolution without any additional therapy. At 6-month follow-up, the blood pressure increased, and imaging revealed a tight stenosis in the left renal artery, which was successfully treated with a stent. In the next days, there was an immediate significant blood pressure reduction.

CONCLUSION

Renal denervation can be complicated by local tissue injury at the ablation sites that could be a possible trigger of late arterial disease.

摘要

目的

描述肾动脉去神经术(RDN)后即刻和随访时对肾动脉的影响。

病例报告

一名 52 岁女性因严重难治性高血压行 RDN。在射频能量输送后即刻,左侧肾动脉出现短暂痉挛,随后无需任何额外治疗即可完全缓解。6 个月随访时,血压升高,影像学显示左侧肾动脉严重狭窄,成功置入支架治疗。随后几天,血压立即显著下降。

结论

肾去神经术可能会导致消融部位的局部组织损伤,这可能是晚期动脉疾病的一个潜在触发因素。

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Eur J Med Res. 2020 Jun 18;25(1):22. doi: 10.1186/s40001-020-00422-5.
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Renal denervation after Symplicity HTN-3: an update.
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Curr Hypertens Rep. 2014 Aug;16(8):460. doi: 10.1007/s11906-014-0460-x.