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The morphology of simian immunodeficiency virus as shown by negative staining electron microscopy.

作者信息

Grief C, Hockley D J, Fromholc C E, Kitchin P A

机构信息

National Institute for Biological Standards and Control, South Mimms, Hertfordshire, U.K.

出版信息

J Gen Virol. 1989 Aug;70 ( Pt 8):2215-9. doi: 10.1099/0022-1317-70-8-2215.

DOI:10.1099/0022-1317-70-8-2215
PMID:2475583
Abstract

Negative staining electron microscopy was used to study sucrose gradient-purified preparations of the simian immunodeficiency virus (SIVmac251). Both isolated and aggregated virus particles were observed together with some free-lying virus cores. The cores were 110 nm long and 25 to 50 nm wide and were mainly conical or wedge-like in shape. Surface projections were seen on the envelope membrane of many of the virus particles; the knobs were approximately 6 nm in length, 10 nm wide and from an end-on view they had a Y or triangular-shaped morphology.

摘要

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