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[早期胃黏液腺癌的临床病理研究]

[A clinicopathological study of early mucinous adenocarcinoma of the stomach].

作者信息

Hosokawa O, Yamamichi N, Yamazaki S, Tsuda J, Watanabe K, Matsuda K

机构信息

Dept. of Surgery, Fukui Prefectural Hospital.

出版信息

Gan No Rinsho. 1989 Aug;35(9):1004-9.

PMID:2475650
Abstract

From 1963 to 1986, 1126 cases (1300 lesions) of early gastric carcinoma were treated at Fukui Prefectural Hospital. Mucinous adenocarcinomas comprised 16 lesions in this series. These cases of mucinous adenocarcinoma were younger than all the other early carcinomas of the stomach and they often were locted in the lower third of the stomach. Macroscopically, most were types "Iia + IIc". Dividing them into 3 grouping: papillary, tubular, and signet ring cell types, depending on the microscopic appearance of the intramucosal carcinoma, the signet ring cell group differed from the other two as to age, macroscopic appearance, and region it occupied. An immunochemical study showed that CA19-9 stained positively in a mucous lake, much like a carcinoma cell, but that CEA stained little.

摘要

1963年至1986年,福井县立医院共治疗了1126例(1300处病灶)早期胃癌患者。本系列中黏液腺癌有16处病灶。这些黏液腺癌病例比所有其他早期胃癌患者年龄更小,且病灶常位于胃的下三分之一处。宏观上,大多数为“Iia + IIc”型。根据黏膜内癌的微观表现将其分为3组:乳头状、管状和印戒细胞型,印戒细胞组在年龄、宏观表现及所占区域方面与其他两组不同。免疫化学研究表明,CA19-9在黏液湖中呈阳性染色,很像癌细胞,但癌胚抗原(CEA)染色较少。

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