糖尿病患者冠状动脉病变的介入性血管重建；住院期间及一年随访
Interventional Revascularization of Coronary Artery Lesions in Diabetic Patients; In-hospital and One Year Follow up.
作者信息
Zibaeenezhad Mohammad Javad, Aslani Amir, Moniri Alireza, Kheiri Mohammad Ali, Heydari Seyed Taghi, Amanat Ahmad, Daneshvar Zahra
机构信息
Cardiovascular Research Center, Shiraz University of Medical Science, Shiraz, IR Iran.
Jahrom University of Medical Science, Jahrom, IR Iran.
出版信息
Int Cardiovasc Res J. 2012 Dec;6(4):113-7. Epub 2012 Dec 15.
BACKGROUND
Diabetes mellitus is a life threatening disease accompanied by several micro- and macro vascular complications. Several modalities are available for interventional revascularization of coronary artery lesions, but their efficacy in diabetic patients is studied only in few patients.
MATERIALS AND METHOD
This study evaluated major in- hospital complications and clinical outcome after one year in 200 consecutive patients who underwent percutaneous Coronary Intervention from 2007 to 2009.
RESULTS
Our findings showed comparable single and 2 vessel stenting, regarding major adverse cardiovascular event in diabetic and nondiabetic patients. In connection with long term and in hospital outcome, no statistically significant difference was found between one and two vessel stenting when drug eluting stent was used in diabetic patients.
CONCLUSION
The use of drug eluting stent in single or two vessel disease of diabetic patients is technically satisfactory and clinically safe and can substitute for coronary artery bypass grafting.
背景
糖尿病是一种危及生命的疾病，伴有多种微血管和大血管并发症。有多种方式可用于冠状动脉病变的介入性血管重建，但它们在糖尿病患者中的疗效仅在少数患者中进行了研究。
材料与方法
本研究评估了2007年至2009年接受经皮冠状动脉介入治疗的200例连续患者一年内的主要院内并发症和临床结局。
结果
我们的研究结果表明，在糖尿病患者和非糖尿病患者中，单支血管和双支血管支架置入术在主要不良心血管事件方面具有可比性。就长期和院内结局而言，当糖尿病患者使用药物洗脱支架时，单支血管和双支血管支架置入术之间未发现统计学上的显著差异。
结论
在糖尿病患者的单支或双支血管病变中使用药物洗脱支架在技术上令人满意且临床安全，可替代冠状动脉旁路移植术。
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