Romanov S P
Neirofiziologiia. 1989;21(3):379-89.
The electron analogue of a neuron working in real time scale is suggested. The sequence of signals' transformation in this analogue is in line with synaptic, postsynaptic membrane and somatic processes. Data on the synapse as on a "key" and on the postsynaptic membrane as on the ion channel with conductivity changed under the influence of a mediator and intracellular potential permit making the neuron analog on the basis of the pulse generator with the possibility to reproduce the synaptic apparatus activity and the neuronal dendrites' structure. The processes of the impulse flow transformation characteristic for neurons of different types, for example motoneurons and Renshow cells are modelled by changing the parameters of the membrane resistance and capacity. The study of simple networks has shown possible to use the suggested analogues for investigating principles of neuronal structure organizations and mechanisms of neuronal interactions, particularly in the motor control system.
本文提出了一种在实时尺度上工作的神经元的电子模拟模型。该模拟模型中信号转换的顺序与突触、突触后膜和体细胞过程一致。关于突触作为“钥匙”以及突触后膜作为在介质和细胞内电位影响下电导率发生变化的离子通道的数据，使得基于脉冲发生器构建神经元模拟模型成为可能，该模型能够再现突触装置的活动和神经元树突的结构。通过改变膜电阻和电容的参数，对不同类型神经元（例如运动神经元和闰绍细胞）特有的冲动流转换过程进行了建模。对简单网络的研究表明，所提出的模拟模型可用于研究神经元结构组织的原理和神经元相互作用的机制，特别是在运动控制系统中。
