Kawai Y, Mori S, Takagi H
First Department of Anatomy, Osaka City University Medical School, Japan.
Neurosci Lett. 1989 Jun 5;101(1):6-10. doi: 10.1016/0304-3940(89)90431-x.
The morphological features of substance P-immunoreactive (SP-IR) structures in the nucleus of the tractus solitarius (NTS) were examined by immunoelectron microscopy combined with an anterograde degeneration study. Vagal afferents were allowed to degenerate by resecting the nodose ganglion two days prior to the examination. SP-IR axon terminals in the ipsilateral NTS were often found to make a synaptic contact with non-reactive dendrites in contact with degenerated terminals. SP-IR terminals also made contact with degenerated terminals, or SP-IR cells in contact with degenerated terminals. These findings suggest a close relationship between SP neuronal structures and vagal afferents in the NTS.
通过免疫电子显微镜结合顺行性变性研究，检查了孤束核（NTS）中P物质免疫反应性（SP-IR）结构的形态学特征。在检查前两天切除结节神经节，使迷走神经传入纤维发生变性。同侧NTS中的SP-IR轴突终末常被发现与接触变性终末的无反应性树突形成突触联系。SP-IR终末也与变性终末接触，或与接触变性终末的SP-IR细胞接触。这些发现提示NTS中SP神经元结构与迷走神经传入纤维之间存在密切关系。
