Hanson Amy L, Ros Simon, Soprano Joyce
From the *Division of Pediatric Emergency Medicine, University of Utah School of Medicine, University of Utah, Salt Lake City, UT; and †Division of Pediatric Emergency Medicine, Stritch School of Medicine, Loyola University Medical Center, Maywood, IL.
Pediatr Emerg Care. 2014 May;30(5):311-4. doi: 10.1097/PEC.0000000000000119.
The primary objective was to determine whether the sitting flexed position yields higher success rates of obtaining cerebrospinal fluid (CSF) for culture. The secondary objectives were to determine whether the sitting flexed position yields higher success rates of obtaining the following: CSF for cell count, non-traumatic CSF, and CSF on the first attempt.
The study investigator performed a retrospective chart review of infants 0 to 365 days of age who had a lumbar puncture (LP) performed from January 1 to December 31 of 2010. Data on the LP position and the number of attempts were abstracted from procedure notes. Twenty-one LPs were excluded because of incomplete data on LP position and/or number of attempts. Spinal fluid count results were obtained from electronic medical records. Non-traumatic LPs were defined in 2 categories: CSF red blood cell counts of 500 cells per cubic millimeter or less and 10,000 cells per cubic millimeter or less.
One hundred thirty-two LPs were included: 30 sitting flexed and 102 lateral flexed. There were no differences in success rates between positions for the primary objective of obtaining CSF for culture and the secondary study objectives of obtaining CSF for cell count and non-traumatic CSF. A significant secondary objective was that operators who performed the LP in the sitting flexed position were more likely to obtain CSF on the first attempt (odds ratio, 2.74; confidence interval, 1.17-6.45).
The sitting flexed position was as successful as the lateral flexed position in the primary objective of obtaining CSF for culture and the secondary objectives of obtaining CSF for cell count and non-traumatic CSF. For the secondary objective of obtaining CSF on the first attempt, the sitting flexed position was associated with a higher rate of obtaining CSF on the first attempt in infants younger than 12 months.
主要目的是确定坐姿屈曲位获取用于培养的脑脊液(CSF)的成功率是否更高。次要目的是确定坐姿屈曲位获取以下物质的成功率是否更高:用于细胞计数的CSF、非创伤性CSF以及首次尝试时获取的CSF。
研究调查员对2010年1月1日至12月31日期间接受腰椎穿刺(LP)的0至365日龄婴儿进行了回顾性病历审查。从操作记录中提取了关于LP体位和尝试次数的数据。由于LP体位和/或尝试次数的数据不完整,排除了21次LP。脑脊液计数结果从电子病历中获取。非创伤性LP分为两类:脑脊液红细胞计数每立方毫米500个细胞或更少以及每立方毫米10,000个细胞或更少。
纳入了132次LP:30次为坐姿屈曲位,102次为侧卧位屈曲位。在获取用于培养的CSF这一主要目标以及获取用于细胞计数的CSF和非创伤性CSF这些次要研究目标方面,不同体位的成功率没有差异。一个显著的次要目标是,采用坐姿屈曲位进行LP的操作人员首次尝试时更有可能获取CSF(优势比,2.74;置信区间,1.17 - 6.45)。
在获取用于培养的CSF这一主要目标以及获取用于细胞计数的CSF和非创伤性CSF这些次要目标方面,坐姿屈曲位与侧卧位屈曲位的成功率相当。对于首次尝试获取CSF这一次要目标,在12个月以下婴儿中,坐姿屈曲位与首次尝试时获取CSF的较高发生率相关。