帕金森病和特发性震颤中震颤的电生理特征。
Electrophysiologic characteristics of tremor in Parkinson's disease and essential tremor.
作者信息
Cichaczewski Ederson, Munhoz Renato P, Maia Joaquim M, Nohama Percy, Nóvak Edison M, Teive Helio A
机构信息
Universidade Tecnológica Federal do Paraná, Curitiba, PR, Brazil.
Associação Paranaense dos Portadores de Parkinsonismo, Curitiba, PR, Brazil.
出版信息
Arq Neuropsiquiatr. 2014 Apr;72(4):301-6. doi: 10.1590/0004-282x20140006.
UNLABELLED
Tremor in essential tremor (ET) and Parkinson's disease (PD) usually present specific electrophysiologic profiles, however amplitude and frequency may have wide variations.
OBJECTIVE
To present the electrophysiologic findings in PD and ET.
METHOD
Patients were assessed at rest, with posture and action. Seventeen patients with ET and 62 with PD were included. PD cases were clustered into three groups: predominant rest tremor; tremor with similar intensity at rest, posture and during kinetic task; and predominant kinetic tremor.
RESULTS
Patients with PD presented tremors with average frequency of 5.29±1.18 Hz at rest, 5.79±1.39 Hz with posture and 6.48±1.34 Hz with the kinetic task. Tremor in ET presented with an average frequency of 5.97±1.1 Hz at rest, 6.18±1 Hz with posture and 6.53±1.2 Hz with kinetic task. Seven (41.2%) also showed rest tremor.
CONCLUSION
The tremor analysis alone using the methodology described here, is not sufficient to differentiate tremor in ET and PD.
未标记
特发性震颤（ET）和帕金森病（PD）中的震颤通常呈现特定的电生理特征，然而其幅度和频率可能有很大差异。
目的
呈现帕金森病和特发性震颤的电生理研究结果。
方法
对患者在静息、姿势和动作状态下进行评估。纳入了17例特发性震颤患者和62例帕金森病患者。帕金森病病例分为三组：以静息震颤为主；静息、姿势和运动任务时震颤强度相似；以运动性震颤为主。
结果
帕金森病患者静息时震颤平均频率为5.29±1.18Hz，姿势时为5.79±1.39Hz，运动任务时为6.48±1.34Hz。特发性震颤患者静息时震颤平均频率为5.97±1.1Hz，姿势时为6.18±1Hz，运动任务时为6.53±1.2Hz。7例（41.2%）还表现出静息震颤。
结论
仅使用此处描述的方法进行震颤分析，不足以区分特发性震颤和帕金森病中的震颤。
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